SCHEMBL1681075

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13491527	0.95	MMP13 (0.61)	MMP13PRKACAPRKXPRKCQROCK1
	SCHEMBL1681116	0.93	ALOX15 (0.58)	MMP13NPC1RAB9APRKACAPRKX
	SCHEMBL13491676	0.92	MMP13 (0.64)	MMP13NPC1RAB9AROCK1ROCK2
	SCHEMBL13491429	0.92	MMP13 (0.55)	MMP13NPC1RAB9ACLK4PDGFRB
	SCHEMBL13491601	0.92	NPC1 (0.59)	MMP13NPC1RAB9ACLK4TP53
	SCHEMBL1681262	0.92	FFAR1 (0.57)	MMP13ROCK2CYP3A4HPGDLMNA
	SCHEMBL1680867	0.90	EGLN1 (0.55)	MMP13RAB9ACYP3A4HPGDLMNA
	SCHEMBL13491492	0.89	MMP13 (0.53)	MMP13RAB9APRKACAPRKXPRKCQ
	SCHEMBL1680991	0.89	MMP13 (0.49)	MMP13RAB9APRKACAPRKXPRKCQ
	SCHEMBL13491455	0.88	NPC1 (0.63)	MMP13NPC1RAB9ACLK4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.