SCHEMBL16808697

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18179364	1.00	ALDH1A1 (0.34)	ALDH1A1LMNASMN1; SMN2OPRL1GAA
	SCHEMBL16808556	1.00	ALDH1A1 (0.34)	ALDH1A1LMNASMN1; SMN2OPRL1GAA
	SCHEMBL16808656	0.82	SMN1; SMN2 (0.37)	ALDH1A1LMNASMN1; SMN2GAATSHR
	SCHEMBL16808546	0.82	SMN1; SMN2 (0.37)	ALDH1A1LMNASMN1; SMN2GAATSHR
	SCHEMBL29418611	0.82	TAAR1 (0.37)	ALDH1A1LMNAOPRL1GAATSHR
	SCHEMBL17119535	0.82	TAAR1 (0.37)	ALDH1A1LMNAOPRL1GAATSHR
	SCHEMBL15551716	0.82	TAAR1 (0.37)	ALDH1A1LMNAOPRL1GAATSHR
	SCHEMBL17093315	0.82	TAAR1 (0.37)	ALDH1A1LMNAOPRL1GAATSHR
	SCHEMBL29015095	0.82	TAAR1 (0.37)	ALDH1A1LMNAOPRL1GAATSHR
	SCHEMBL29418820	0.82	TAAR1 (0.37)	ALDH1A1LMNAOPRL1GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.