SCHEMBL1680901

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13450865	0.85	ROCK2 (0.55)	EPHX2ROCK2TP53MAPT
	SCHEMBL1681123	0.83	EPHX2 (0.45)	EPHX2ROCK2THRBTP53POLB
	SCHEMBL1681110	0.79	ROCK1 (0.45)	ROCK2THRBHPGDTP53POLB
	SCHEMBL1680949	0.79	EGLN1 (0.54)	ROCK2THRBHPGDTP53MAPT
	SCHEMBL1681193	0.78	NPC1 (0.56)	ROCK2HPGDTP53
	SCHEMBL1680986	0.78	NAMPT (0.53)	—
	SCHEMBL13450239	0.74	EPHX2 (0.62)	EPHX2ROCK2
	SCHEMBL13450238	0.73	L3MBTL1 (0.58)	EPHX2ROCK2LMNA
	SCHEMBL1681142	0.73	EPHX2 (0.55)	EPHX2ROCK2HPGDMAPTLMNA
	SCHEMBL13450997	0.73	L3MBTL1 (0.69)	EPHX2ROCK2HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.