SCHEMBL16809332

SCHEMBL16809332

COc1ccc2c(c1)oc1cc3c(cc12)oc1cc(O)ccc13

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.68
KDM4E B2RXH2 6/20 0.62
ALDH1A1 P00352 6/20 0.62
HSD17B10 Q99714 3/20 0.62
LMNA P02545 2/20 0.62
ALOX15 P16050 1/20 0.62
HTT P42858 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
MEN1 O00255 3/20 0.58
TP53 P04637 3/20 0.58
CYP3A4 P08684 3/20 0.58
KMT2A Q03164 3/20 0.58
CYP2C9 P11712 2/20 0.58
CYP2C19 P33261 2/20 0.58
TNKS O95271 1/20 0.58
TNKS2 Q9H2K2 1/20 0.58
HPGD P15428 3/20 0.56
CYP2D6 P10635 1/20 0.56
NOD2 Q9HC29 1/20 0.55
NPC1 O15118 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10649359 0.96 MAPT (0.71) MAPTKDM4EALDH1A1HSD17B10LMNA
SCHEMBL8867576 0.87 MAOA (0.69) MAPTKDM4EALDH1A1HSD17B10SMN1; SMN2
SCHEMBL7097279 0.85 KDM4E (0.69) MAPTKDM4EALDH1A1HSD17B10LMNA
SCHEMBL16810179 0.82 DYRK1A (0.52) MAPTKDM4EALDH1A1HSD17B10LMNA
SCHEMBL29853647 0.81 MAPT (0.89) MAPTKDM4EALDH1A1HSD17B10LMNA
SCHEMBL26780124 0.81 MAPT (0.89) MAPTKDM4EALDH1A1HSD17B10LMNA
SCHEMBL803412 0.81 MAPT (1.00) MAPTKDM4EALDH1A1HSD17B10LMNA
SCHEMBL29853434 0.81 MAPT (1.00) MAPTKDM4EALDH1A1HSD17B10LMNA
SCHEMBL3874542 0.79 KDM4E (1.00) MAPTKDM4EALDH1A1HSD17B10LMNA
SCHEMBL29600967 0.79 KDM4E (1.00) MAPTKDM4EALDH1A1HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150166561-A1 ORGANIC THIN FILM TRANSISTOR, ORGANIC SEMICONDUCTOR THIN FILM, AND ORGANIC SEMICONDUCTOR MATERIAL FUJIFILM CORPORATION (JP) 2015-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150166561-A1 ORGANIC THIN FILM TRANSISTOR, ORGANIC SEMICONDUCTOR THIN FILM, AND ORGANIC SEMICONDUCTOR MATERIAL TRMT1L, APOL1, TLL1 MAPT 3067/4885KDM4E 2184/4885ALDH1A1 3732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.