SCHEMBL16809474

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18169340	0.86	PPARG (0.36)	PPARGRECQLALDH1A1MAPTPOLB
	SCHEMBL16809555	0.83	PPARG (0.35)	PPARGRECQLALDH1A1MAPTPOLB
	SCHEMBL16809653	0.82	KCNH2 (0.35)	PPARGRECQLALDH1A1MAPTPOLB
	SCHEMBL16809670	0.80	SIGMAR1 (0.52)	RECQLALDH1A1MAPTPOLBGAA
	SCHEMBL16797613	0.79	SIGMAR1 (0.40)	SIGMAR1CYP1A2CYP3A4CYP2C9TSHR
	SCHEMBL16809703	0.78	CA2 (0.51)	CYP1A2TSHRNFKB1CYP2C19
	SCHEMBL16809680	0.76	SIGMAR1 (0.42)	SIGMAR1
	SCHEMBL19894287	0.73	CA2 (0.38)	POLBKDM4ECYP1A2TSHRNFKB1
	SCHEMBL16797607	0.72	ABCB1 (0.35)	RECQLMAPTPOLBGAAL3MBTL1
	SCHEMBL18169305	0.72	AKR1B1 (0.33)	ALDH1A1GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.