SCHEMBL16809653

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16809555	0.99	PPARG (0.35)	KCNH2GRIN2BPOLBGAAMAPK1
	SCHEMBL18169340	0.86	PPARG (0.36)	KCNH2GRIN2BPOLBGAAALDH1A1
	SCHEMBL16809474	0.82	PPARG (0.37)	KCNH2GRIN2BPOLBGAAALDH1A1
	SCHEMBL16809424	0.80	KCNH2 (0.55)	KCNH2GRIN2BPOLBGAAALDH1A1
	SCHEMBL16809563	0.79	KCNH2 (0.53)	KCNH2GRIN2BPOLBGAAALDH1A1
	SCHEMBL16809663	0.78	SIGMAR1 (0.41)	SIGMAR1HPGDTSHRHTR1AADRA1B
	SCHEMBL16809702	0.77	CA2 (0.50)	MAPK1ALDH1A1MAPTL3MBTL1SIGMAR1
	SCHEMBL16809543	0.77	SIGMAR1 (0.42)	SIGMAR1HPGDTSHRHTR1AADRA1B
	SCHEMBL16809562	0.76	SIGMAR1 (0.44)	L3MBTL1SIGMAR1
	SCHEMBL18169277	0.76	CA2 (0.51)	SIGMAR1HTR1AADRA1BADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.