Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16797641 | 0.81 | MAPT (0.47) | GAAMAPTTDP2POLBALDH1A1 | |
| SCHEMBL12949113 | 0.72 | GAA (0.47) | GAAMAPTTDP2POLBALDH1A1 | |
| SCHEMBL9202048 | 0.71 | BCHE (0.50) | GAAMAPTTDP2POLBALDH1A1 | |
| SCHEMBL10665110 | 0.71 | ADRA1A (0.54) | GAAMAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL13637390 | 0.71 | RORC (0.54) | GAAMAPTTDP2POLBALDH1A1 | |
| SCHEMBL30562928 | 0.71 | RORC (0.54) | GAAMAPTTDP2POLBALDH1A1 | |
| SCHEMBL6367769 | 0.70 | ALDH1A1 (0.42) | GAAMAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL14095369 | 0.70 | ALDH1A1 (0.42) | GAAMAPTPOLBALDH1A1L3MBTL1 | |
| SCHEMBL8615947 | 0.70 | ALDH1A1 (0.47) | GAAMAPTTDP2POLBALDH1A1 | |
| SCHEMBL2709952 | 0.70 | CA12 (0.73) | GAAMAPTALDH1A1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015088272-A9 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2015-10-01 | — | — | WO | disclosed |
| WO-2015088272-A1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2015-06-18 | — | — | WO | disclosed |