SCHEMBL16797641

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4138312	0.84	ALDH1A1 (0.43)	MAPTGAAALDH1A1HPGDNPC1
	SCHEMBL10352340	0.83	ALDH1A1 (0.45)	MAPTALDH1A1HPGDNPC1RAB9A
	SCHEMBL16809602	0.81	GAA (0.44)	MAPTTDP2POLBGAAALDH1A1
	SCHEMBL9988677	0.81	TSHR (0.53)	MAPTTDP2POLBGAAALDH1A1
	SCHEMBL9988676	0.81	TSHR (0.53)	MAPTTDP2POLBGAAALDH1A1
	SCHEMBL11104138	0.80	KMT2A (0.49)	MAPTGAAALDH1A1HPGDL3MBTL1
	SCHEMBL16809480	0.80	PTGS1 (0.42)	MAPTPOLBHPGDNPC1RAB9A
	SCHEMBL11778977	0.76	AKR1C3 (0.58)	MAPTALDH1A1HPGDNPC1RAB9A
	SCHEMBL11106829	0.76	ALOX15 (0.54)	POLBGAAHPGDCA1CA2
	SCHEMBL16504443	0.76	ADRA2A (0.51)	MAPTTDP2POLBGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.