Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8622290 | 0.98 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTTHRBMEN1 | |
| SCHEMBL23414454 | 0.83 | ADRA1A (0.59) | ALDH1A1MAPTMEN1BLMKMT2A | |
| SCHEMBL9988677 | 0.81 | TSHR (0.53) | ALDH1A1GAAMAPTTHRBMEN1 | |
| SCHEMBL9988676 | 0.81 | TSHR (0.53) | ALDH1A1GAAMAPTTHRBMEN1 | |
| SCHEMBL25609289 | 0.80 | THRB (0.40) | ALDH1A1THRBMEN1KMT2AKDM4E | |
| SCHEMBL8226247 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1BLMKMT2A | |
| SCHEMBL12949113 | 0.80 | GAA (0.47) | ALDH1A1GAAMAPTTHRBMEN1 | |
| SCHEMBL9207541 | 0.79 | ADRA2A (0.57) | ALDH1A1GAAMAPTTHRBMEN1 | |
| SCHEMBL11122389 | 0.79 | AKR1C3 (0.60) | ALDH1A1GAAMAPTTHRBMEN1 | |
| SCHEMBL11791007 | 0.77 | GRM1 (0.51) | ALDH1A1GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839799-A1 | 2-HYDROXYPHENYLALKYLAMINE DERIVATIVES AND MAILLARD REACTION INHIBITORS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-05-06 | — | — | EP | disclosed |