Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.61 |
| ▸ | DRD3 | P35462 | 3/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.47 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16825744 | 0.88 | CHIT1 (0.51) | DRD3HRH1DRD2CHIT1CHIA | |
| SCHEMBL16826343 | 0.84 | LTA4H (0.64) | SLC6A2SLC6A4DRD3DRD2CHIT1 | |
| SCHEMBL16825780 | 0.84 | LMNA (0.64) | SLC6A2SLC6A4HRH3DRD2 | |
| SCHEMBL16825821 | 0.83 | CHIT1 (0.52) | DRD3HRH3HRH1DRD2CHIT1 | |
| SCHEMBL16825820 | 0.83 | CHIT1 (0.52) | DRD3DRD2CHIT1CHIA | |
| SCHEMBL16826340 | 0.83 | CHIA (0.67) | SLC6A2SLC6A4DRD3CHIT1CHIA | |
| SCHEMBL18135548 | 0.83 | CHIT1 (0.52) | DRD3HRH3DRD2CHIT1CHIA | |
| SCHEMBL16825681 | 0.83 | CHIT1 (0.52) | SLC6A2SLC6A4DRD3HRH3HRH1 | |
| SCHEMBL16826405 | 0.82 | DRD2 (0.59) | DRD3HRH3HRH1DRD2 | |
| SCHEMBL16825679 | 0.81 | HTR1A (0.54) | DRD3HRH1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082805-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | The Institute For Drug Delivery (US) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015095701-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | THE INSTITUTE FOR DRUG DELIVERY (US) | 2015-06-25 | — | — | WO | disclosed |