Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | ESRRB | O95718 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESRRA | P11474 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16825872 | 1.00 | ABCB1 (0.53) | ABCB1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL16825792 | 0.81 | DRD2 (0.53) | ABCB1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL16846231 | 0.81 | DRD2 (0.53) | ABCB1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL16846206 | 0.81 | DRD2 (0.53) | ABCB1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL376336 | 0.77 | ALDH1A1 (0.60) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL8380925 | 0.77 | ABCB1 (0.54) | ABCB1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8380927 | 0.77 | ABCB1 (0.54) | ABCB1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL16825885 | 0.76 | SIGMAR1 (0.55) | ABCB1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL18129169 | 0.76 | SIGMAR1 (0.55) | ABCB1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL20425431 | 0.76 | L3MBTL1 (0.55) | ABCB1CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082805-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | The Institute For Drug Delivery (US) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015095701-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | THE INSTITUTE FOR DRUG DELIVERY (US) | 2015-06-25 | — | — | WO | disclosed |