Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CCL2 | P13500 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19630560 | 0.74 | HTR2A (0.39) | CYP2D6KDM4ELMNAHSD17B10HTR2A | |
| SCHEMBL29386036 | 0.74 | HTR2A (0.39) | CYP2D6KDM4ELMNAHSD17B10HTR2A | |
| Hydrochloric Acid SCHEMBL16394143 | 0.73 | HTR6 (0.32) | HTR6 | |
| SCHEMBL7946917 | 0.72 | ALDH1A1 (0.36) | HSD17B10TP53CYP3A4MEN1KMT2A | |
| SCHEMBL313823 | 0.71 | HTR6 (0.32) | CYP2D6HTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL30769631 | 0.71 | HTR2A (0.36) | CYP2D6KDM4ELMNAHSD17B10HTR2A | |
| Hydrochloric Acid SCHEMBL30769837 | 0.71 | HTR2A (0.36) | CYP2D6KDM4ELMNAHSD17B10HTR2A | |
| SCHEMBL2830663 | 0.71 | HTR2C (0.37) | CYP2D6KDM4ELMNAHSD17B10HTR2A | |
| Hydrochloric Acid SCHEMBL30769736 | 0.71 | HTR2A (0.36) | CYP2D6KDM4ELMNAHSD17B10HTR2A | |
| SCHEMBL2830664 | 0.69 | PRCP (0.39) | CYP2D6KDM4ELMNAHSD17B10HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3755705-A1 | CATALYSTS, CATALYST SYSTEMS, AND METHODS FOR USING THE SAME | ExxonMobil Chemical Patents Inc. (US) | 2020-12-30 | — | — | EP | disclosed |
| US-20200339712-A1 | Catalysts, Catalyst Systems, and Methods for Using the Same | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2020-10-29 | — | — | US | disclosed |
| WO-2019160710-A1 | CATALYSTS, CATALYST SYSTEMS, AND METHODS FOR USING THE SAME | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2019-08-22 | — | — | WO | disclosed |
| US-9944665-B2 | Bridged bis(indenyl) transitional metal complexes, production, and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2018-04-17 | — | — | US | disclosed |
| EP-3083649-A1 | BRIDGED BIS(INDENYL) TRANSITIONAL METAL COMPLEXES, PRODUCTION, AND USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2016-10-26 | — | — | EP | disclosed |
| US-20150183893-A1 | Bridged Bis(Indenyl) Transitional Metal Complexes, Production, and Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-07-02 | — | — | US | disclosed |
| WO-2015095188-A1 | BRIDGED BIS(INDENYL) TRANSITIONAL METAL COMPLEXES, PRODUCTION, AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183893-A1 | Bridged Bis(Indenyl) Transitional Metal Complexes, Production, and Use Thereof | XRN2, XRCC6, INTS9 | CYP2D6 1806/4885KDM4E 2238/4885LMNA 339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.