Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19570447 | 0.88 | APOBEC3G (0.40) | APOBEC3GGFERLMNATDP1MAPT | |
| SCHEMBL166328 | 0.85 | MAPT (0.48) | APOBEC3GGFERLMNATDP1MAPT | |
| SCHEMBL8232792 | 0.82 | APOBEC3G (0.48) | APOBEC3GGFERLMNATDP1MAPT | |
| SCHEMBL165618 | 0.80 | APOBEC3G (0.44) | APOBEC3GGFERLMNATDP1MAPT | |
| SCHEMBL19265137 | 0.80 | AVPR2 (0.48) | APOBEC3GGFERLMNATDP1MAPT | |
| SCHEMBL460084 | 0.79 | AVPR2 (0.51) | AVPR2AVPR1A | |
| Water SCHEMBL2512796 | 0.79 | APOBEC3G (0.43) | APOBEC3GGFERLMNATDP1MAPT | |
| SCHEMBL409762 | 0.79 | AVPR2 (0.51) | AVPR2AVPR1A | |
| SCHEMBL256612 | 0.79 | AVPR2 (0.51) | AVPR2AVPR1A | |
| SCHEMBL16542299 | 0.78 | APOBEC3G (0.45) | APOBEC3GGFERLMNATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021259852-A1 | PROCESS FOR PREPARING 5-(ALKOXYCARBONYL)-AND 5-(CARBOXAMIDE)-1-ARYL-1,2,4-TRIAZOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-12-30 | — | — | WO | disclosed |
| US-11091463-B2 | Amide-substituted pyridinyltriazole derivatives and uses thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-08-17 | — | — | US | disclosed |
| EP-3452463-B1 | AMIDE-SUBSTITUTED PYRIDINYLTRIAZOLE DERIVATIVES AND USES THEREOF | Bayer Pharma AG (DE) | 2021-03-24 | — | — | EP | disclosed |
| US-10927098-B2 | Hydroxyalkyl-substituted triazole derivatives and uses thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-02-23 | — | — | US | disclosed |
| US-10815205-B2 | Amide-substituted phenyltriazole derivatives and uses thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-10-27 | — | — | US | disclosed |
| US-10800746-B2 | Oxoalkyl-substituted phenyltriazole derivatives and uses thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-10-13 | — | — | US | disclosed |
| US-20200299271-A1 | METHOD FOR PRODUCING 5-HYDROXYALKYL-SUBSTITUTED 1-PHENYL-1,2,4- TRIAZOLE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-09-24 | — | — | US | disclosed |
| US-10703742-B2 | Method for producing 5-hydroxyalkyl-substituted 1-phenyl-1,2,4-triazole derivatives | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-07-07 | — | — | US | disclosed |
| EP-3452470-B1 | AMIDE-SUBSTITUTED PHENYLTRIAZOLE DERIVATIVES AND USES THEREOF | Bayer Pharma AG (DE) | 2020-03-18 | — | — | EP | disclosed |
| EP-3452457-B1 | OXOALKYL-SUBSTITUTED PHENYLTRIAZOLE DERIVATIVES AND USES THEREOF | Bayer Pharma AG (DE) | 2020-03-18 | — | — | EP | disclosed |
| WO-2011104322-A1 | BISARYL-BONDED ARYLTRIAZOLONES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-09-01 | — | — | WO | disclosed |
| WO-2011023703-A1 | HETEROCYCLIC-SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-03-03 | — | — | WO | disclosed |
| WO-2011023703-A1 | HETEROCYCLIC-SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-03-03 | — | — | WO | disclosed |
| US-20100261771-A1 | SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-10-14 | — | — | US | disclosed |
| US-20100261771-A1 | SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-10-14 | — | — | US | disclosed |
| US-20100261771-A1 | SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-10-14 | — | — | US | disclosed |
| WO-2010105770-A1 | SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010105750-A1 | TRIAZOLE DERIVATIVES AS VASOPRESSIN-RECEPTOR INHIBITORS FOR TREATING CARDIAC INSUFFICIENCY | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010105750-A1 | TRIAZOLE DERIVATIVES AS VASOPRESSIN-RECEPTOR INHIBITORS FOR TREATING CARDIAC INSUFFICIENCY | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010063402-A1 | SUBSTITUTED BENZYL AND PHENYLSULFONYL TRIAZOLONES, AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927098-B2 | Hydroxyalkyl-substituted triazole derivatives and uses thereof | LIPG, PLIN3, FABP3 | APOBEC3G 2788/4885GFER 1662/4885LMNA 1209/4885 |
| US-10815205-B2 | Amide-substituted phenyltriazole derivatives and uses thereof | AADAC, GLS, NAT1 | APOBEC3G 3267/4885GFER 2476/4885LMNA 1670/4885 |
| US-10800746-B2 | Oxoalkyl-substituted phenyltriazole derivatives and uses thereof | AADAC, REN, PKD1 | APOBEC3G 1688/4885GFER 1748/4885LMNA 1653/4885 |
| US-20100261771-A1 | SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF | AADAC, NAT1, TNNT2 | APOBEC3G 3004/4885GFER 2590/4885LMNA 726/4885 |
| US-10703742-B2 | Method for producing 5-hydroxyalkyl-substituted 1-phenyl-1,2,4-triazole derivatives | CYP1A1, H1-3, H1-0 | APOBEC3G 1590/4885GFER 3102/4885LMNA 1609/4885 |
| US-11091463-B2 | Amide-substituted pyridinyltriazole derivatives and uses thereof | AADAC, GLS, PDXK | APOBEC3G 2789/4885GFER 2245/4885LMNA 1110/4885 |
| US-20200299271-A1 | METHOD FOR PRODUCING 5-HYDROXYALKYL-SUBSTITUTED 1-PHENYL-1,2,4- TRIAZOLE DERIVATIVES | CYP1A1, H1-3, H1-0 | APOBEC3G 1590/4885GFER 3102/4885LMNA 1609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.