Sulfuric Acid

Sulfuric Acid

SCHEMBL1683534

C=C(C)C(=O)OCC[N+](C)(CC)CC.O=S(=O)(O)O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 known ✓ P11229 7/20 0.41
CHRM3 known ✓ P20309 6/20 0.41
CHRM2 known ✓ P08172 5/20 0.38
SCN1A known ✓ P35498 2/20 0.37
SCN2A known ✓ Q99250 2/20 0.37
SCN3A known ✓ Q9NY46 2/20 0.37
THRB P10828 1/20 0.47
TSHR P16473 3/20 0.46
CHRM4 P08173 5/20 0.41
CHRM5 P08912 4/20 0.39
PGR P06401 1/20 0.36
HTR1A P08908 1/20 0.36
CHRNB2 P17787 1/20 0.36
TBXA2R P21731 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA7 P36544 1/20 0.36
CHRNA4 P43681 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CHRNA10 Q9GZZ6 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL475669 0.93 THRB (0.53) THRBTSHRCHRM1CHRM3CHRM4
SCHEMBL1597440 0.93 THRB (0.53) THRBTSHRCHRM1CHRM3CHRM4
Bromide SCHEMBL246208 0.91 THRB (0.52) THRBTSHRCHRM1CHRM3CHRM4
SCHEMBL630863 0.88 THRB (0.42) THRBTSHRCHRM1CHRM3CHRM4
Sulfuric Acid SCHEMBL11784028 0.87 THRB (0.47) THRBTSHRCHRM1CHRM3CHRM4
Sulfuric Acid SCHEMBL3202107 0.84 CHRM5 (0.57) THRBTSHRCHRM1CHRM3CHRM4
Hydrochloric Acid SCHEMBL5455297 0.83 TSHR (0.58) THRBTSHRCHRM1CHRM3CHRM4
SCHEMBL27862861 0.83 TSHR (0.58) THRBTSHRCHRM1CHRM3CHRM4
SCHEMBL895605 0.83 CHRM1 (0.40) THRBTSHRCHRM1CHRM3CHRM4
Hydrochloric Acid SCHEMBL14335996 0.83 TSHR (0.45) THRBTSHRCHRM1CHRM3CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8680038-B2 Copolymer containing zwitterionic units and other units, composition comprising the copolymer, and use RHODIA OPERATIONS (FR) 2014-03-25 US claimed
EP-1966259-B1 COPOLYMER CONTAINING ZWITTERIONIC UNITS AND OTHER UNITS, COMPOSITION COMPRISING THE COPOLYMER, AND USE RHODIA OPERATIONS (FR) 2012-04-18 EP claimed
US-20090197791-A1 COPOLYMER CONTAINING ZWITTERIONIC UNITS AND OTHER UNITS, COMPOSITION COMPRISING THE COPOLYMER, AND USE RHODIA RECHERCHES ET TECHNOLOGIES (FR) 2009-08-06 US claimed
US-8680038-B2 Copolymer containing zwitterionic units and other units, composition comprising the copolymer, and use RHODIA OPERATIONS (FR) 2014-03-25 US disclosed
US-8637622-B2 Copolymer including betaine units and hydrophobic and/or amphiphilic units, method for preparing same and uses thereof RHODIA OPERATIONS (FR) 2014-01-28 US disclosed
US-20110092634-A1 POLYMERIC MICROGEL COMPRISING CATIONIC UNITS RHODIA OPERATIONS (FR) 2011-04-21 US disclosed
US-20100093874-A1 COPOLYMER INCLUDING BETAINE UNITS AND HYDROPHOBIC AND/OR AMPHIPHILIC UNITS, METHOD FOR PREPARING SAME AND USES THEREOF RHODIA OPERATIONS (FR) 2010-04-15 US disclosed
US-20090197791-A1 COPOLYMER CONTAINING ZWITTERIONIC UNITS AND OTHER UNITS, COMPOSITION COMPRISING THE COPOLYMER, AND USE RHODIA RECHERCHES ET TECHNOLOGIES (FR) 2009-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100093874-A1 COPOLYMER INCLUDING BETAINE UNITS AND HYDROPHOBIC AND/OR AMPHIPHILIC UNITS, METHOD FOR PREPARING SAME AND USES THEREOF SLC6A12, BHMT, PHOSPHO1 CHRM1 590/4885CHRM3 1171/4885CHRM2 790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.