Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | CTSG | P08311 | 2/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.36 |
| ▸ | CMA1 | P23946 | 2/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16820710 | 0.99 | ACACB (0.38) | ACACBCA2LMNAL3MBTL1PRSS1 | |
| Hydrochloric Acid SCHEMBL16820709 | 0.99 | ACACB (0.38) | ACACBCA2LMNAL3MBTL1PRSS1 | |
| SCHEMBL16820675 | 0.88 | LMNA (0.41) | ACACBCA2LMNAL3MBTL1PRSS1 | |
| SCHEMBL16820674 | 0.88 | LMNA (0.41) | ACACBCA2LMNAL3MBTL1PRSS1 | |
| SCHEMBL20299901 | 0.87 | ACACB (0.41) | ACACBCA2RARBRARG | |
| SCHEMBL254640 | 0.87 | ACACB (0.41) | ACACBCA2RARBRARG | |
| SCHEMBL16840371 | 0.85 | MMP2 (0.40) | ACACBCA2LMNAL3MBTL1TAS1R3 | |
| SCHEMBL15235731 | 0.85 | ADRB2 (0.38) | ACACBCA2LMNAL3MBTL1 | |
| SCHEMBL3017864 | 0.84 | ACACB (0.46) | ACACBTAS1R3TAS1R1 | |
| SCHEMBL16840374 | 0.83 | ITGB1 (0.40) | ACACBCA2LMNAL3MBTL1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150175530-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2015-06-25 | — | — | US | disclosed |
| US-20150175530-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2015-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175530-A1 | ANTIBACTERIAL AGENTS | MRPL21, ABCB11, LSS | ACACB 3647/4885CA2 3990/4885LMNA 3308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.