Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 7/20 | 0.38 |
| ▸ | MPO | P05164 | 5/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4911919 | 0.80 | PTGS1 (0.44) | SNCASLC6A4HDAC3HDAC1HDAC2 | |
| SCHEMBL1684159 | 0.73 | GPR84 (0.36) | SNCA | |
| Ethane SCHEMBL2954432 | 0.72 | GPR84 (0.37) | SNCAMPOHDAC3HDAC1HDAC2 | |
| SCHEMBL2944828 | 0.69 | MAP3K5 (0.35) | — | |
| Ethane SCHEMBL2948593 | 0.66 | HTR2B (0.34) | SNCAHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL28007656 | 0.65 | HCAR2 (0.40) | SLC6A4HTR2BMEN1LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL28007658 | 0.64 | HCAR2 (0.39) | SLC6A4HTR2BMEN1LMNACYP1A2 | |
| SCHEMBL4913061 | 0.63 | SMN1; SMN2 (0.42) | SLC6A4LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4911912 | 0.63 | ANO1 (0.39) | — | |
| SCHEMBL28007337 | 0.61 | GABRG2 (0.43) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041512-A2 | COMPOSITIONS AND METHODS FOR TREATING MLV-INFECTION, AND PREVENTING AND TREATING MLV-INITIATED DISEASES | EMORY UNIVERSITY (US) | 2011-04-07 | — | — | WO | disclosed |