Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.30 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.30 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1684162 | 0.84 | GPR84 (0.35) | GPR84 | |
| SCHEMBL1684208 | 0.75 | ALDH1A1 (0.39) | HTR1A | |
| SCHEMBL1684160 | 0.73 | SNCA (0.38) | SNCA | |
| Ethane SCHEMBL2954432 | 0.67 | GPR84 (0.37) | GPR84SNCA | |
| SCHEMBL2944828 | 0.64 | MAP3K5 (0.35) | — | |
| SCHEMBL2951250 | 0.63 | POLB (0.38) | — | |
| SCHEMBL1684121 | 0.62 | RIPK1 (0.46) | — | |
| SCHEMBL28819880 | 0.61 | GABRA1 (0.46) | GPR84 | |
| SCHEMBL1684143 | 0.59 | RIPK1 (0.42) | — | |
| SCHEMBL1684122 | 0.58 | RIPK1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041512-A2 | COMPOSITIONS AND METHODS FOR TREATING MLV-INFECTION, AND PREVENTING AND TREATING MLV-INITIATED DISEASES | EMORY UNIVERSITY (US) | 2011-04-07 | — | — | WO | disclosed |