Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 13/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 13/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 12/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 12/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 11/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 10/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28007656 | 0.85 | HCAR2 (0.40) | NPC1MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL28007658 | 0.84 | HCAR2 (0.39) | NPC1MTNR1AMTNR1B | |
| SCHEMBL2806960 | 0.76 | GABRG2 (0.50) | GABRG2GABRB3GABRA1GABRA2GABRA5 | |
| SCHEMBL16610221 | 0.74 | MTNR1B (0.38) | MTNR1AMTNR1B | |
| SCHEMBL4915074 | 0.74 | GABRA1 (0.46) | GABRG2GABRB3GABRA1GABRA2GABRA5 | |
| SCHEMBL28819880 | 0.73 | GABRA1 (0.46) | GABRG2GABRB3GABRA1GABRA2GABRA5 | |
| SCHEMBL18508705 | 0.69 | GABRA1 (0.41) | GABRG2GABRB3GABRA1GABRA2GABRA5 | |
| SCHEMBL2297259 | 0.68 | GABRG2 (0.52) | GABRG2GABRB3GABRA1GABRA2GABRA5 | |
| SCHEMBL12526818 | 0.67 | REN (0.44) | GABRG2GABRB3GABRA1GABRA2GABRA5 | |
| SCHEMBL1046830 | 0.67 | MTNR1B (0.45) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104640847-B | Novel Renin Inhibitors | 上海医药集团股份有限公司 | 2019-10-15 | — | — | CN | disclosed |
| CN-104640847-A | Novel Renin Inhibitors | SHANGHAI PHARMACEUTICALS HOLDING CO LTD | 2015-05-20 | — | — | CN | disclosed |