Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24910485 | 0.84 | TSHR (0.46) | — | |
| SCHEMBL21074376 | 0.82 | GPR3 (0.35) | GPR3GPR183 | |
| SCHEMBL13341163 | 0.76 | GPR55 (0.33) | GPR3 | |
| SCHEMBL17031874 | 0.76 | GPR183 (0.32) | GPR3GPR183 | |
| SCHEMBL16072583 | 0.74 | CYP1A2 (0.32) | GPR3 | |
| SCHEMBL24986409 | 0.74 | PTGS2 (0.38) | GPR3 | |
| SCHEMBL13341077 | 0.74 | GABRA1 (0.32) | GPR3 | |
| SCHEMBL23480218 | 0.74 | CYP3A4 (0.36) | — | |
| SCHEMBL15369494 | 0.74 | GPR3 (0.31) | GPR3 | |
| SCHEMBL10273089 | 0.74 | PTGS1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180092902-A1 | CCR6 COMPOUNDS | CHEMOCENTRYX, INC. | 2018-04-05 | — | — | US | disclosed |
| US-9795599-B2 | CCR6 compounds | CHEMOCENTRYX, INC. (US) | 2017-10-24 | — | — | US | disclosed |
| US-9795599-B2 | CCR6 compounds | CHEMOCENTRYX, INC. (US) | 2017-10-24 | — | — | US | disclosed |
| US-20160296508-A1 | CCR6 COMPUNDS | CHEMOCENTRYX, INC. | 2016-10-13 | — | — | US | disclosed |
| US-9340509-B2 | CCR6 compounds | CHEMOCENTRYX, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-20150175547-A1 | CCR6 COMPOUNDS | CHEMOCENTRYX, INC. | 2015-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160296508-A1 | CCR6 COMPUNDS | CCR6, CCR1, CCR4 | GPR3 2324/4885GPR183 1610/4885 |
| US-20180092902-A1 | CCR6 COMPOUNDS | CCR6, CCR1, CCR4 | GPR3 1117/4885GPR183 956/4885 |
| US-20150175547-A1 | CCR6 COMPOUNDS | CCR6, CCR1, CCR4 | GPR3 1117/4885GPR183 956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.