Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.33 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17031874 | 0.87 | GPR183 (0.32) | GPR3TSHRGPR183 | |
| SCHEMBL16072583 | 0.86 | CYP1A2 (0.32) | GPR3CYP1A2KIF11 | |
| SCHEMBL15369494 | 0.86 | GPR3 (0.31) | GPR3 | |
| SCHEMBL16843333 | 0.82 | GPR3 (0.33) | GPR3GPR183 | |
| SCHEMBL25028967 | 0.74 | ULK1 (0.33) | GPR3TSHRNOTUM | |
| SCHEMBL18307738 | 0.73 | TSHR (0.33) | TSHR | |
| SCHEMBL8239476 | 0.72 | TSHR (0.39) | GPR3CTNNB1WNT3ATSHRNOTUM | |
| SCHEMBL13058897 | 0.71 | CA2 (0.31) | TSHRALDH1A1CA2 | |
| SCHEMBL24401069 | 0.71 | GPR55 (0.32) | GPR3 | |
| SCHEMBL19485824 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10786494-B2 | CCR6 compounds | CHEMOCENTRYX, INC. (US) | 2020-09-29 | — | — | US | disclosed |
| US-20190167659-A1 | CCR6 COMPOUNDS | CHEMOCENTRYX, INC. | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190167659-A1 | CCR6 COMPOUNDS | CCR6, CCR1, CCR4 | GPR3 1117/4885CTNNB1 3229/4885WNT3A 4225/4885 |
| US-10786494-B2 | CCR6 compounds | CCR6, CCR1, CCR4 | GPR3 1117/4885CTNNB1 3229/4885WNT3A 4225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.