Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 3/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1282800 | 0.87 | MLYCD (0.52) | MLYCDOPRL1OPRD1HSD11B1OPRM1 | |
| SCHEMBL3422626 | 0.86 | MLYCD (0.53) | MLYCDOPRL1OPRD1HSD11B1OPRK1 | |
| SCHEMBL1684394 | 0.76 | ALDH1A1 (0.38) | OPRL1OPRD1OPRM1OPRK1HDAC6 | |
| SCHEMBL1282234 | 0.76 | MLYCD (0.50) | MLYCDOPRD1HSD11B1OPRM1OPRK1 | |
| SCHEMBL8366154 | 0.75 | OPRL1 (0.56) | MLYCDOPRL1OPRD1HSD11B1OPRM1 | |
| SCHEMBL2702494 | 0.73 | OPRD1 (0.47) | MLYCDOPRL1OPRD1KCNH2 | |
| SCHEMBL2702717 | 0.73 | PKM (0.54) | MLYCDOPRL1OPRD1 | |
| SCHEMBL1684410 | 0.73 | MLYCD (0.49) | MLYCDOPRL1OPRD1OPRM1 | |
| SCHEMBL2722547 | 0.73 | AKR1C1 (0.57) | MLYCDOPRL1OPRD1HSD11B1OPRM1 | |
| SCHEMBL501923 | 0.73 | AKR1C1 (0.57) | MLYCDOPRL1OPRD1HSD11B1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012045124-A1 | BACTERIA TOPOISOMERASE II INHIBITING 2-ETHYLCARBAMOYLAMINO-1, 3-BENZOTHIAZOL-5-YLS | BIOTA EUROPE LTD (GB) | 2012-04-12 | — | — | WO | disclosed |