Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13434090 | 0.83 | L3MBTL1 (0.51) | HSD11B1OPRM1OPRD1 | |
| SCHEMBL10722280 | 0.83 | HSD11B1 (0.70) | HSD11B1ADORA2ABRD4 | |
| SCHEMBL13674323 | 0.79 | HSD11B1 (0.69) | HSD11B1 | |
| SCHEMBL13431647 | 0.79 | HSD11B1 (0.69) | HSD11B1 | |
| SCHEMBL4486060 | 0.79 | HSD11B1 (0.61) | HSD11B1OPRM1OPRD1ADORA2ABRD4 | |
| SCHEMBL1353088 | 0.78 | LMNA (0.65) | HSD11B1ADORA2ABRD4 | |
| SCHEMBL96038 | 0.76 | HSD11B1 (0.62) | HSD11B1ADORA2ABRD4 | |
| SCHEMBL4139952 | 0.75 | L3MBTL1 (0.62) | HSD11B1ADORA2A | |
| SCHEMBL27537635 | 0.75 | PARP10 (0.43) | GPR119OPRM1OPRD1OPRK1CYP2C9 | |
| SCHEMBL3710538 | 0.75 | HSD11B1 (0.51) | HSD11B1ADORA2AF2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2306837-A1 | PESTCIDAL ACTIVE MIXTURES COMPRISING ISOXAZOLINE COMPOUNDS I | BASF SE (DE) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010003923-A1 | PESTCIDAL ACTIVE MIXTURES COMPRISING ISOXAZOLINE COMPOUNDS I | BASF SE (DE) | 2010-01-14 | — | — | WO | disclosed |