Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16852370 | 0.93 | CTSL (0.43) | CTSLCTSSCTSKGABRA1GABRB2 | |
| SCHEMBL16852399 | 0.92 | CTSL (0.38) | CTSLCTSSCTSKGABRA1GABRB2 | |
| SCHEMBL16852390 | 0.92 | CTSL (0.43) | CTSLCTSSCTSKPPARDS1PR1 | |
| SCHEMBL16852391 | 0.91 | THRA (0.42) | CTSLCTSSCTSKPPARDS1PR1 | |
| SCHEMBL16852385 | 0.91 | THRB (0.37) | CTSLCTSSCTSKGABRA1GABRB2 | |
| SCHEMBL16852364 | 0.90 | CCNT1 (0.38) | CTSLCTSSCTSKGABRA1GABRB2 | |
| SCHEMBL16852421 | 0.90 | CTSL (0.45) | CTSLCTSSCTSKGABRA1GABRB2 | |
| SCHEMBL16852386 | 0.90 | THRB (0.39) | CTSLCTSSCTSKALOX5PPARD | |
| SCHEMBL17359289 | 0.89 | CTSL (0.44) | CTSLCTSSCTSKGABRA1GABRB2 | |
| SCHEMBL16852433 | 0.88 | GABRA1 (0.38) | GABRA1GABRB2CCNT1CDK9NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951274-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2018-04-24 | — | — | US | disclosed |
| US-20150175884-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| US-20150175884-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |