Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 4/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16852384 | 0.96 | NAAA (0.41) | NAAACTSLCTSSCTSKKDM1A | |
| SCHEMBL16852373 | 0.95 | NAAA (0.40) | NAAACTSLCTSSCTSKKDM1A | |
| SCHEMBL16852371 | 0.92 | S1PR1 (0.40) | NAAACTSLCTSSCTSKMGLL | |
| SCHEMBL16852421 | 0.92 | CTSL (0.45) | NAAACTSLCTSSCTSKKDM1A | |
| SCHEMBL16852399 | 0.91 | CTSL (0.38) | NAAACTSLCTSSCTSKGABRA1 | |
| SCHEMBL16852380 | 0.91 | THRA (0.40) | CTSLCTSSCTSKL3MBTL1MGLL | |
| SCHEMBL16852382 | 0.90 | THRA (0.42) | CTSLCTSSCTSKMGLLS1PR1 | |
| SCHEMBL16852430 | 0.88 | THRB (0.40) | CTSLCTSSCTSKL3MBTL1MGLL | |
| SCHEMBL16852400 | 0.88 | S1PR1 (0.39) | CTSLCTSSCTSKL3MBTL1MGLL | |
| SCHEMBL16852398 | 0.88 | MGLL (0.46) | NAAAPTGS2PTGS1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951274-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2018-04-24 | — | — | US | disclosed |
| US-9951274-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2018-04-24 | — | — | US | disclosed |
| US-20150175884-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| US-20150175884-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |