SCHEMBL16865403

SCHEMBL16865403

O=C1NC(=O)C(S)(Cc2ccccc2)C(=O)N1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP9 P14780 10/20 0.50
MMP2 P08253 9/20 0.50
MMP13 P45452 8/20 0.50
MMP8 P22894 6/20 0.50
CYP3A4 P08684 2/20 0.42
ADAM17 P78536 2/20 0.41
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
CYP2C9 P11712 2/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP1A2 P05177 1/20 0.40
HPGD P15428 1/20 0.40
CYP2C19 P33261 1/20 0.40
CACNA1B Q00975 1/20 0.40
APBA1 Q02410 1/20 0.40
MMP3 P08254 2/20 0.39
CACNA1F O60840 1/20 0.38
HTR2A P28223 1/20 0.38
HRH1 P35367 1/20 0.38
SCN1A P35498 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5448618 0.81 MMP9 (0.64) MMP9MMP2MMP13MMP8CYP3A4
SCHEMBL7475063 0.76 MMP9 (0.50) MMP9MMP2MMP13MMP8CYP3A4
SCHEMBL11276893 0.76 MMP9 (0.50) MMP9MMP2MMP13MMP8CYP3A4
SCHEMBL16865428 0.76 MMP9 (0.56) MMP9MMP2MMP13MMP8CYP3A4
SCHEMBL6267425 0.74 MMP13 (0.55) MMP9MMP2MMP13MMP8CYP3A4
SCHEMBL4174555 0.72 CYP3A4 (0.49) MMP9MMP2MMP13MMP8CYP3A4
SCHEMBL17294170 0.72 MMP9 (0.46) MMP9MMP2MMP13MMP8CYP3A4
SCHEMBL18344443 0.69 MMP9 (0.88) MMP9MMP2MMP13MMP8ALDH1A1
SCHEMBL7097777 0.69 ALDH1A1 (0.60) MMP9MMP2MMP13MMP8CYP3A4
SCHEMBL15972776 0.69 ALDH1A1 (0.60) MMP9MMP2MMP13MMP8CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150185368-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE SAME, AND COMPOUND C1R, C1S, C3AR1 MMP9 2110/4885MMP2 2359/4885MMP13 375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.