Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | BLM | P54132 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CASP1 | P29466 | 3/20 | 0.51 |
| ▸ | CASP7 | P55210 | 2/20 | 0.51 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | PADI1 | Q9ULC6 | 3/20 | 0.47 |
| ▸ | PADI3 | Q9ULW8 | 3/20 | 0.47 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.47 |
| ▸ | PADI2 | Q9Y2J8 | 3/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | S100A4 | P26447 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15855938 | 0.77 | MAPT (0.57) | MAOAMAOBMAPTBLMSMN1; SMN2 | |
| SCHEMBL7649527 | 0.75 | CDC25B (0.44) | MAPTCDC25BPADI1PADI3PADI4 | |
| SCHEMBL31112247 | 0.74 | MAOA (0.77) | MAOAMAOBMAPTBLMSMN1; SMN2 | |
| SCHEMBL16685145 | 0.74 | MAOA (0.70) | MAOAMAOBMAPTBLMSMN1; SMN2 | |
| SCHEMBL30616365 | 0.74 | MAOA (0.86) | MAOAMAOBMAPTBLMSMN1; SMN2 | |
| SCHEMBL20618218 | 0.74 | MAOA (0.77) | MAOAMAOBMAPTBLMSMN1; SMN2 | |
| SCHEMBL8417659 | 0.74 | MAOA (0.86) | MAOAMAOBMAPTBLMSMN1; SMN2 | |
| SCHEMBL11088784 | 0.73 | CDC25B (0.61) | MAOAMAOBMAPTBLMSMN1; SMN2 | |
| Caulibugulone A SCHEMBL2555738 | 0.73 | MAPT (0.63) | MAOAMAOBMAPTBLMSMN1; SMN2 | |
| SCHEMBL29429719 | 0.73 | PTPN1 (0.68) | MAOAMAOBMAPTBLMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927085-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | HUEN CO., LTD. (KR) | 2021-02-23 | — | — | US | disclosed |
| EP-3091005-B1 | 1,2-NAPHTHOQUINONE DERIVATIVE AND METHOD FOR PREPARING SAME | HUEN CO LTD (KR) | 2020-11-11 | — | — | EP | disclosed |
| US-20160376243-A1 | 1,2-NAPHTHOQUINONE BASED DERIVATIVE AND METHOD OF PREPARING THE SAME | KT&G LIFE SCIENCES CORPORATION (KR) | 2016-12-29 | — | — | US | disclosed |
| US-20160376243-A1 | 1,2-NAPHTHOQUINONE BASED DERIVATIVE AND METHOD OF PREPARING THE SAME | KT&G LIFE SCIENCES CORPORATION (KR) | 2016-12-29 | — | — | US | disclosed |
| EP-3091005-A1 | 1,2-NAPHTHOQUINONE DERIVATIVE AND METHOD FOR PREPARING SAME | KT&G Life Sciences Corporation (KR) | 2016-11-09 | — | — | EP | disclosed |
| WO-2015102369-A1 | 1,2-NAPHTHOQUINONE DERIVATIVE AND METHOD FOR PREPARING SAME | 주식회사 케이티앤지생명과학 | 2015-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927085-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | UGT1A6, CYP2D6, SLC5A1 | MAOA 2707/4885MAOB 2266/4885MAPT 182/4885 |
| US-20160376243-A1 | 1,2-NAPHTHOQUINONE BASED DERIVATIVE AND METHOD OF PREPARING THE SAME | CYP2S1, SLC5A1, CYP2D6 | MAOA 2544/4885MAOB 2223/4885MAPT 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.