Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | BLM | P54132 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CASP1 | P29466 | 3/20 | 0.57 |
| ▸ | CASP7 | P55210 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15690474 | 0.82 | HDAC6 (0.62) | MAPTBLMSMN1; SMN2TP53CYP3A4 | |
| Caulibugulone A SCHEMBL2555738 | 0.77 | MAPT (0.63) | MAPTBLMSMN1; SMN2TP53CYP3A4 | |
| SCHEMBL18347803 | 0.74 | S100A4 (0.58) | MAPTBLMSMN1; SMN2TDP2G6PD | |
| SCHEMBL8654523 | 0.70 | MAPT (0.69) | MAPTBLMSMN1; SMN2TP53CYP3A4 | |
| SCHEMBL8102460 | 0.69 | CDC25A (0.47) | MAPTSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL15855938 | 0.69 | MAPT (0.57) | MAPTBLMSMN1; SMN2TP53CYP3A4 | |
| SCHEMBL8654199 | 0.68 | MAPT (0.55) | MAPTBLMSMN1; SMN2TP53CYP3A4 | |
| SCHEMBL8417659 | 0.67 | MAOA (0.86) | MAPTBLMSMN1; SMN2TP53CYP3A4 | |
| SCHEMBL30616365 | 0.67 | MAOA (0.86) | MAPTBLMSMN1; SMN2TP53CYP3A4 | |
| SCHEMBL8655228 | 0.67 | MAPT (0.69) | MAPTBLMSMN1; SMN2TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927085-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | HUEN CO., LTD. (KR) | 2021-02-23 | — | — | US | disclosed |
| EP-3091005-B1 | 1,2-NAPHTHOQUINONE DERIVATIVE AND METHOD FOR PREPARING SAME | HUEN CO LTD (KR) | 2020-11-11 | — | — | EP | disclosed |
| US-20160376243-A1 | 1,2-NAPHTHOQUINONE BASED DERIVATIVE AND METHOD OF PREPARING THE SAME | KT&G LIFE SCIENCES CORPORATION (KR) | 2016-12-29 | — | — | US | disclosed |
| US-20160376243-A1 | 1,2-NAPHTHOQUINONE BASED DERIVATIVE AND METHOD OF PREPARING THE SAME | KT&G LIFE SCIENCES CORPORATION (KR) | 2016-12-29 | — | — | US | disclosed |
| EP-3091005-A1 | 1,2-NAPHTHOQUINONE DERIVATIVE AND METHOD FOR PREPARING SAME | KT&G Life Sciences Corporation (KR) | 2016-11-09 | — | — | EP | disclosed |
| WO-2015102369-A1 | 1,2-NAPHTHOQUINONE DERIVATIVE AND METHOD FOR PREPARING SAME | 주식회사 케이티앤지생명과학 | 2015-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927085-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | UGT1A6, CYP2D6, SLC5A1 | MAPT 182/4885BLM 970/4885SMN1; SMN2 1275/4885 |
| US-20160376243-A1 | 1,2-NAPHTHOQUINONE BASED DERIVATIVE AND METHOD OF PREPARING THE SAME | CYP2S1, SLC5A1, CYP2D6 | MAPT 129/4885BLM 884/4885SMN1; SMN2 1188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.