SCHEMBL9568580

SCHEMBL9568580

C=CC(=O)Nc1ccc(S(=O)(=O)NCCCC)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 2/20 0.58
LMNA P02545 8/20 0.58
ALDH1A1 P00352 4/20 0.56
KMT2A Q03164 3/20 0.56
HTT P42858 3/20 0.56
MEN1 O00255 2/20 0.56
THRA P10827 1/20 0.56
THRB P10828 1/20 0.56
POLB P06746 2/20 0.55
SMN1; SMN2 Q16637 4/20 0.55
MAPT P10636 3/20 0.54
TP53 P04637 1/20 0.54
GPR55 Q9Y2T6 1/20 0.53
NAMPT P43490 1/20 0.52
GAA P10253 2/20 0.50
NPY1R P25929 1/20 0.50
NPY2R P49146 1/20 0.50
ALOX12 P18054 1/20 0.50
PKM P14618 1/20 0.49
MAPK1 P28482 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1688071 0.92 TGM2 (0.61) TGM2LMNAALDH1A1KMT2AMEN1
SCHEMBL9568839 0.86 TGM2 (0.65) TGM2LMNAALDH1A1KMT2AMEN1
SCHEMBL4594909 0.83 POLB (0.79) LMNAALDH1A1KMT2AHTTMEN1
SCHEMBL396729 0.82 LMNA (0.55) TGM2LMNAALDH1A1KMT2AHTT
SCHEMBL396728 0.81 POLB (0.58) LMNAALDH1A1KMT2AHTTMEN1
SCHEMBL19262185 0.80 LMNA (0.63) LMNAALDH1A1KMT2AHTTMEN1
SCHEMBL4066416 0.79 POLB (0.77) LMNAALDH1A1KMT2AHTTMEN1
Bromide SCHEMBL28122058 0.79 THRB (0.62) TGM2LMNATHRATHRBGAA
SCHEMBL9568766 0.78 THRB (0.55) LMNAALDH1A1KMT2AHTTMEN1
SCHEMBL3813625 0.78 TGM2 (0.71) TGM2LMNAKMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed