SCHEMBL1688196

SCHEMBL1688196

CCCCS(=O)(=O)NC(=O)CCCCCCCCCCCCCCCc1nnn[nH]1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARG P37231 8/20 0.36
PLA2G2C Q5R387 1/20 0.34
ITGB3 P05106 1/20 0.33
ITGAV P06756 1/20 0.33
HSP90AA1 P07900 1/20 0.33
EPHX2 P34913 1/20 0.32
CXCR2 P25025 1/20 0.32
FAAH O00519 1/20 0.32
DEGS1 O15121 1/20 0.32
PTGES O14684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12673964 1.00 PPARG (0.36) PPARGPLA2G2CITGB3ITGAVHSP90AA1
SCHEMBL13880584 0.94 CXCR2 (0.36) PPARGPLA2G2CHSP90AA1EPHX2CXCR2
SCHEMBL13892164 0.91 FAAH (0.38) EPHX2FAAH
SCHEMBL13113625 0.90 CASP2 (0.40) EPHX2FAAH
SCHEMBL16093010 0.90 CASP2 (0.40) EPHX2FAAH
SCHEMBL13880602 0.90 MTNR1A (0.33) PLA2G2CCXCR2
SCHEMBL12809270 0.90 FAAH (0.34) PPARGEPHX2FAAH
SCHEMBL1688321 0.90 FAAH (0.38) PPARGITGB3ITGAVFAAH
SCHEMBL12641022 0.89 PPARG (0.30) PPARG
SCHEMBL13694066 0.89 PPARG (0.30) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120088716-A1 Polypeptide Protracting Tags NOVO NORDISK A/S (DK) 2012-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088716-A1 Polypeptide Protracting Tags VIP, FGB, NPPA PPARG 1969/4885PLA2G2C 1461/4885ITGB3 672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.