SCHEMBL16883233

SCHEMBL16883233

CC1(C)c2ccccc2-c2ccc(N(c3ccc4sc5ccccc5c4c3)c3ccc4c5ccccc5c5ccccc5c4c3)cc21

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.34
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PDK2 Q15119 3/20 0.33
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALK Q9UM73 1/20 0.31
PTPN7 P35236 1/20 0.31
DUSP3 P51452 1/20 0.31
PTPN12 Q05209 1/20 0.31
PTPN22 Q9Y2R2 1/20 0.31
PTGIR P43119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22057732 0.98 ALDH1A1 (0.35) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL21392634 0.96 GPR3 (0.37) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL22057726 0.94 ALDH1A1 (0.36) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL16428478 0.93 ALK (0.31) ALK
SCHEMBL16883133 0.93 ALK (0.31) ALK
SCHEMBL21141221 0.93 GPR3 (0.34) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL17126506 0.93 ALDH1A1 (0.36) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL16124274 0.93 PDK2 (0.36) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL17690168 0.93 GPR3 (0.34) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL17126501 0.92 PDK2 (0.32) GPR3ALDH1A1MAPTHPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10985325-B2 Aromatic amine derivative, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2021-04-20 US disclosed
US-10862045-B2 Amine-based compound and organic light-emitting element comprising same LG CHEM, LTD. 2020-12-08 US disclosed
EP-3336077-B1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2019-09-11 EP disclosed
EP-3336077-A2 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2018-06-20 EP disclosed
EP-3312167-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Idemitsu Kosan Co., Ltd. (JP) 2018-04-25 EP disclosed
WO-2017052138-A2 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2017-03-30 WO disclosed
EP-2940097-A1 ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE INCLUDING SAME Cheil Industries Inc. (KR) 2015-11-04 EP disclosed
US-20150280136-A1 ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-10-01 US disclosed
US-20150280136-A1 ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-10-01 US disclosed
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-09-17 US disclosed
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-09-17 US disclosed
EP-2891653-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Idemitsu Kosan Co., Ltd (JP) 2015-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME RER1, H1-2, NAP1L1 GPR3 1294/4885ALDH1A1 30/4885MAPT 1642/4885
US-10985325-B2 Aromatic amine derivative, and organic electroluminescent element using same RER1, H1-2, NAP1L1 GPR3 1294/4885ALDH1A1 30/4885MAPT 1642/4885
US-10862045-B2 Amine-based compound and organic light-emitting element comprising same EML4, OR10J3, AOC2 GPR3 1720/4885ALDH1A1 291/4885MAPT 76/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.