Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.39 |
| ▸ | FEN1 | P39748 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16885099 | 0.84 | CYP1A2 (0.40) | USP1ALOX5APFEN1RAB9AMAPT | |
| SCHEMBL16666266 | 0.84 | DDR1 (0.44) | USP1ALOX5APFEN1 | |
| SCHEMBL16885086 | 0.75 | NPC1 (0.40) | ESR1ALOX5APFEN1ATRALDH1A1 | |
| SCHEMBL16872708 | 0.74 | USP1 (0.42) | USP1ALOX5APFEN1MAPTALDH1A1 | |
| SCHEMBL16885090 | 0.74 | PDE5A (0.47) | ALDH1A1CYP1A2 | |
| SCHEMBL15426362 | 0.73 | KDM4E (0.55) | RAB9AMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL15426342 | 0.73 | NLRP3 (0.45) | RAB9AMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL15426370 | 0.73 | SMN1; SMN2 (0.46) | RAB9AMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL19525379 | 0.73 | ESR1 (0.36) | USP1ESR1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL17689696 | 0.72 | NPC1 (0.51) | RAB9AMAPTSMN1; SMN2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9328121-B1 | Fused heterocyclic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-05-03 | — | — | US | disclosed |
| US-20160102100-A1 | FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2016-04-14 | — | — | US | disclosed |
| US-9260436-B2 | Fused heterocyclic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-02-16 | — | — | US | disclosed |
| US-20150191474-A1 | FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160102100-A1 | FUSED HETEROCYCLIC COMPOUND | NR4A1, CYP4B1, NR1H4 | USP1 2651/4885ESR1 114/4885ALOX5AP 1753/4885 |
| US-20150191474-A1 | FUSED HETEROCYCLIC COMPOUND | NR4A1, NR0B1, NR0B2 | USP1 2314/4885ESR1 213/4885ALOX5AP 2352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.