SCHEMBL31228131

SCHEMBL31228131

O[C@@H]1[C@H](O)[C@@H](CI)O[C@H]1n1ccc2c(Cl)ncnc21

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ ADK P55263 4/20 0.59
▸ PRMT5 O14744 1/20 0.53
▸ WDR77 Q9BQA1 1/20 0.53
▸ SLC29A1 Q99808 1/20 0.51
▸ METTL3 Q86U44 1/20 0.51
▸ METTL14 Q9HCE5 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1689441 0.90 METTL3 (0.52) ADKPRMT5WDR77SLC29A1METTL3
SCHEMBL1689438 0.90 METTL3 (0.52) ADKPRMT5WDR77SLC29A1METTL3
SCHEMBL10160817 0.89 ADK (0.64) ADKSLC29A1METTL3METTL14
SCHEMBL1797344 0.89 ADK (0.64) ADKSLC29A1METTL3METTL14
SCHEMBL10131093 0.89 ADK (0.64) ADKSLC29A1METTL3METTL14
SCHEMBL13005628 0.89 ADK (0.64) ADKSLC29A1METTL3METTL14
SCHEMBL14440901 0.88 ADK (0.63) ADKSLC29A1METTL3METTL14
SCHEMBL14440630 0.88 ADK (0.63) ADKSLC29A1METTL3METTL14
SCHEMBL19696624 0.83 ADK (0.54) ADKPRMT5WDR77METTL3METTL14
SCHEMBL23544706 0.81 ADK (0.53) ADKMETTL3METTL14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 — — EP disclosed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 — — WO disclosed
Send feedback