SCHEMBL169052

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5874074	0.85	ESR1 (0.48)	ESR1ESR2ABHD6GAAHPGD
	SCHEMBL176110	0.83	ESR1 (0.47)	ESR1ESR2ABHD6GAAHPGD
	SCHEMBL166530	0.82	ALDH1A1 (0.48)	GAAHPGDMEN1KMT2ARAB9A
	SCHEMBL3434544	0.81	ABHD6 (0.53)	ESR1ESR2ABHD6GAAHPGD
	SCHEMBL13833745	0.78	MMP13 (0.42)	ESR1ESR2HPGDMEN1KMT2A
	SCHEMBL117485	0.78	ESR1 (0.48)	ESR1ESR2ABHD6HPGDMEN1
	SCHEMBL13076095	0.78	ESR1 (0.45)	ESR1ESR2ABHD6HPGDMEN1
	SCHEMBL3435000	0.77	ESR1 (0.44)	ESR1ESR2ABHD6GAARAB9A
	SCHEMBL5781997	0.77	ESR1 (0.43)	ESR1ESR2HPGDMEN1KMT2A
	SCHEMBL169273	0.77	PDK2 (0.41)	ESR1ESR2ABHD6GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.