SCHEMBL169096

SCHEMBL169096

C[C@H](N)C(=O)NC(=O)[C@H](C)N

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC15A1 P46059 1/20 0.58
DPP4 P27487 2/20 0.50
TAAR1 Q96RJ0 2/20 0.39
DPP8 Q6V1X1 2/20 0.38
DPP7 Q9UHL4 2/20 0.38
PAX8 Q06710 1/20 0.36
XIAP P98170 1/20 0.36
BIRC2 Q13490 1/20 0.36
SLC7A5 Q01650 1/20 0.36
FAP Q12884 1/20 0.36
DPP9 Q86TI2 1/20 0.36
CTRB1 P17538 4/20 0.35
IDO1 P14902 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9115106 0.85
SCHEMBL29634918 0.85
SCHEMBL29616787 0.85
SCHEMBL19115938 0.85
SCHEMBL20717738 0.85
SCHEMBL23691240 0.85
SCHEMBL15385288 0.85
SCHEMBL17920013 0.81 SLC15A1 (0.44) SLC15A1DPP4TAAR1DPP8DPP7
SCHEMBL13521929 0.81 SLC15A1 (0.44) SLC15A1DPP4TAAR1DPP8DPP7
SCHEMBL12488822 0.81 SLC15A1 (0.44) SLC15A1DPP4TAAR1DPP8DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230233436-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH OLSEN ELISE A (US) 2023-07-27 US disclosed
US-20210220248-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH OLSEN, Elise 2021-07-22 US disclosed
US-20200330479-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR LOSS USING NON-NATURALLY OCCURRING PROSTAGLANDINS THE PROCTER & GAMBLE COMPANY 2020-10-22 US disclosed
US-20190314259-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH DUKE UNIVERSITY 2019-10-17 US disclosed
US-20190175475-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR LOSS USING NON-NATURALLY OCCURRING PROSTAGLANDINS THE PROCTER & GAMBLE COMPANY 2019-06-13 US disclosed
US-10159634-B2 Compositions and methods for inhibiting hair growth Olsen, Elise A. (US) 2018-12-25 US disclosed
US-20180064622-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH DUKE UNIVERSITY 2018-03-08 US disclosed
US-9877908-B2 Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives DUKE UNIVERSITY (US) 2018-01-30 US disclosed
US-20170348214-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR LOSS USING NON-NATURALLY OCCURRING PROSTAGLANDINS THE PROCTER & GAMBLE COMPANY 2017-12-07 US disclosed
US-20170239160-A1 COSMETIC AND PHARMACEUTICAL COMPOSITIONS AND METHODS USING 2-DECARBOXY-2-PHOSPHINICO DERIVATIVES THE PROCTER & GAMBLE COMPANY 2017-08-24 US disclosed
CN-1201459-A Novel pyridonecarboxylic acid derivative or salt thereof, and antibacterial agent containing same as active ingredient WAKUNAGA PHARMA CO LTD (JP) 1998-12-09 CN disclosed
EP-0787720-A1 NOVEL PYRIDONECARBOXYLATE DERIVATIVE OR SALT THEREOF AND ANTIBACTERIAL CONTAINING THE SAME AS ACTIVE INGREDIENT WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1997-08-06 EP disclosed
EP-0470578-B1 Novel tricyclic compound or salts thereof, method for producing the same and antimicrobial agent containing the same WAKUNAGA SEIYAKU KK (JP) 1996-11-06 EP disclosed
EP-0700912-A1 QUINOLONE DERIVATIVE OR SALT THEREOF, AND ANTIBACTERIAL CONTAINING THE SAME WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1996-03-13 EP disclosed
US-5412098-A Quinolone derivative or salt thereof and antibacterial containing the same WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1995-05-02 US disclosed
US-5399553-A Oral absorbability WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1995-03-21 US disclosed
EP-0596126-A1 NOVEL QUINOLONE DERIVATIVE OR SALT THEREOF AND ANTIBACTERIAL CONTAINING THE SAME WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1994-05-11 EP disclosed
US-5254685-A Tricyclic compound or salts thereof, method for producing the same and antimicrobial agent containing the same WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1993-10-19 US disclosed
CN-1059144-A New tricyclic compound or its salt, prepare their method and contain their antiseptic-germicide WAKUNAGA SEIYAKU KK (JP) 1992-03-04 CN disclosed
EP-0470578-A1 Novel tricyclic compound or salts thereof, method for producing the same and antimicrobial agent containing the same WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1992-02-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190175475-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR LOSS USING NON-NATURALLY OCCURRING PROSTAGLANDINS PTGES, PTGS1, PTGS2 SLC15A1 2894/4885DPP4 4557/4885TAAR1 3095/4885
US-20180064622-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH PTGIR, MC1R, PTGFR SLC15A1 2263/4885DPP4 4597/4885TAAR1 1048/4885
US-20230233436-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH PTGIR, MC1R, PTGFR SLC15A1 2263/4885DPP4 4597/4885TAAR1 1048/4885
US-20210220248-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH PTGIR, MC1R, PTGFR SLC15A1 2263/4885DPP4 4597/4885TAAR1 1048/4885
US-20170348214-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR LOSS USING NON-NATURALLY OCCURRING PROSTAGLANDINS PTGES, PTGS1, PTGS2 SLC15A1 2894/4885DPP4 4557/4885TAAR1 3095/4885
US-20170239160-A1 COSMETIC AND PHARMACEUTICAL COMPOSITIONS AND METHODS USING 2-DECARBOXY-2-PHOSPHINICO DERIVATIVES BMP2, PLOD2, PTGDR2 SLC15A1 1848/4885DPP4 2431/4885TAAR1 3076/4885
US-20200330479-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR LOSS USING NON-NATURALLY OCCURRING PROSTAGLANDINS PTGES, PTGS1, PTGS2 SLC15A1 2894/4885DPP4 4557/4885TAAR1 3095/4885
US-20190314259-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH PTGIR, MC1R, PTGFR SLC15A1 2263/4885DPP4 4597/4885TAAR1 1048/4885
US-10159634-B2 Compositions and methods for inhibiting hair growth PTGIR, MC1R, PTGFR SLC15A1 2263/4885DPP4 4597/4885TAAR1 1048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.