Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167931 | 0.92 | P2RX3 (0.31) | P2RX3P2RX2 | |
| SCHEMBL165542 | 0.92 | DHFR (0.40) | P2RX3P2RX2DHFR | |
| SCHEMBL166574 | 0.83 | ALDH1A1 (0.39) | — | |
| SCHEMBL165193 | 0.81 | ALDH1A1 (0.36) | P2RX3P2RX2GABRA1GABRB1 | |
| SCHEMBL166973 | 0.80 | DHFR (0.37) | DHFR | |
| SCHEMBL166582 | 0.80 | — | — | |
| SCHEMBL10341247 | 0.79 | TSHR (0.31) | — | |
| SCHEMBL31261127 | 0.74 | HTT (0.37) | P2RX3P2RX2DHFR | |
| SCHEMBL21808365 | 0.74 | HTT (0.37) | P2RX3P2RX2DHFR | |
| SCHEMBL341228 | 0.74 | CA1 (0.35) | P2RX3P2RX2GABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144467-A1 | COMPOSITIONS USEFUL IN GOLF BALLS | THE HANSON GROUP, LLC (US) | 2010-06-10 | — | — | US | claimed |
| WO-2008150865-A2 | COMPOSITIONS USEFUL IN GOLF BALLS | THE HANSON GROUP LLC (US) | 2008-12-11 | — | — | WO | claimed |
| EP-2638088-B1 | HALOGENATION OF 4,4'-METHYLENE-BIS-ANILINES | LONZA AG (CH) | 2015-11-18 | — | — | EP | disclosed |
| US-8557947-B2 | Compositions useful in golf balls | THE HANSON GROUP, LLC (US) | 2013-10-15 | — | — | US | disclosed |
| EP-2638088-A1 | HALOGENATION OF 4,4'-METHYLENE-BIS-ANILINES | Lonza Ltd (CH) | 2013-09-18 | — | — | EP | disclosed |
| US-20130053185-A1 | Compositions Useful in Golf Balls | FOREMOST GOLF MANUFACTURING LTD. (TW) | 2013-02-28 | — | — | US | disclosed |
| US-8324336-B2 | Compositions useful in golf balls | THE HANSON GROUP, LLC (US) | 2012-12-04 | — | — | US | disclosed |
| WO-2012028323-A1 | HALOGENATION OF 4,4'-METHYLENE-BIS-ANILINES | LONZA LTD (CH) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012028323-A1 | HALOGENATION OF 4,4'-METHYLENE-BIS-ANILINES | LONZA LTD (CH) | 2012-03-08 | — | — | WO | disclosed |
| US-20100144467-A1 | COMPOSITIONS USEFUL IN GOLF BALLS | THE HANSON GROUP, LLC (US) | 2010-06-10 | — | — | US | disclosed |
| WO-2008150865-A2 | COMPOSITIONS USEFUL IN GOLF BALLS | THE HANSON GROUP LLC (US) | 2008-12-11 | — | — | WO | disclosed |
| US-4950792-A | CHAIN LENGTHENING, CROSSLINKING AGENT FOR POLYURETHANES | LONZA LTD. (CH) | 1990-08-21 | — | — | US | disclosed |
| EP-0220641-A1 | Substituted p,p'-methylene-bis-anilines | LONZA AG (CH) | 1987-05-06 | — | — | EP | disclosed |