Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 5/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ICMT | O60725 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15880164 | 1.00 | KDM5A (0.47) | KDM5AFAAHDNM1POLBPOLA1 | |
| SCHEMBL19032474 | 1.00 | KDM5A (0.47) | KDM5AFAAHDNM1POLBPOLA1 | |
| SCHEMBL19032444 | 1.00 | KDM5A (0.47) | KDM5AFAAHDNM1POLBPOLA1 | |
| SCHEMBL8335342 | 1.00 | KDM5A (0.47) | KDM5AFAAHDNM1POLBPOLA1 | |
| Hydrochloric Acid SCHEMBL27082309 | 0.98 | KDM5A (0.46) | KDM5AFAAHDNM1POLBPOLA1 | |
| SCHEMBL19032377 | 0.96 | KDM5A (0.45) | KDM5AFAAHDNM1POLBPOLA1 | |
| SCHEMBL19032563 | 0.96 | KDM5A (0.45) | KDM5AFAAHDNM1POLBPOLA1 | |
| SCHEMBL18954314 | 0.96 | KDM5A (0.45) | KDM5AFAAHDNM1POLBPOLA1 | |
| SCHEMBL19032471 | 0.96 | KDM5A (0.45) | KDM5AFAAHDNM1POLBPOLA1 | |
| SCHEMBL8337930 | 0.96 | KDM5A (0.47) | KDM5AFAAHDNM1POLBPOLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220265857-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2022-08-25 | — | — | US | disclosed |
| EP-3386484-B1 | COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX INC (US) | 2022-03-30 | — | — | EP | disclosed |
| US-11285222-B2 | Compositions and methods for delivery of agents | MODERNATX, INC. (US) | 2022-03-29 | — | — | US | disclosed |
| US-20200206362-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | Moderna TX, Inc. (US) | 2020-07-02 | — | — | US | disclosed |
| US-20200206362-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | Moderna TX, Inc. (US) | 2020-07-02 | — | — | US | disclosed |
| US-10556018-B2 | Compositions and methods for delivery of agents | ARES CAPITAL CORPORATION, AS AGENT | 2020-02-11 | — | — | US | disclosed |
| US-10556018-B2 | Compositions and methods for delivery of agents | ARES CAPITAL CORPORATION, AS AGENT | 2020-02-11 | — | — | US | disclosed |
| EP-2900681-B1 | PHARMACEUTICAL COMPOSITION COMPRISING LIPOPHILIC NUCLEOSIDES | IONOVATION GMBH (DE) | 2019-07-10 | — | — | EP | disclosed |
| US-20190175633-A1 | REACTIVE, LIPOPHILIC NUCLEOSIDE BUILDING BLOCKS FOR THE SYNTHESIS OF HYDROPHOBIC NUCLEIC ACIDS | IONOVATION GMBH (DE) | 2019-06-13 | — | — | US | disclosed |
| US-20190117798-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2019-04-25 | — | — | US | disclosed |
| US-20180028664-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2018-02-01 | — | — | US | disclosed |
| US-20180028664-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2018-02-01 | — | — | US | disclosed |
| US-9737613-B2 | Colloid bonded medicinal compounds | B. BRAUN MELSUNGEN AG (DE) | 2017-08-22 | — | — | US | disclosed |
| WO-2017099823-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX, INC. (US) | 2017-06-15 | — | — | WO | disclosed |
| WO-2017099823-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX, INC. (US) | 2017-06-15 | — | — | WO | disclosed |
| US-20150291649-A1 | 5-Fluorouracil Derivatives | B. BRAUN MELSUNGEN AG (DE) | 2015-10-15 | — | — | US | disclosed |
| US-20150240295-A1 | REACTIVE, LIPOPHILIC NUCLEOSIDE BUILDING BLOCKS FOR THE SYNTHESIS OF HYDROPHOBIC NUCLEIC ACIDS | IONOVATION GMBH (DE) | 2015-08-27 | — | — | US | disclosed |
| US-20150240295-A1 | REACTIVE, LIPOPHILIC NUCLEOSIDE BUILDING BLOCKS FOR THE SYNTHESIS OF HYDROPHOBIC NUCLEIC ACIDS | IONOVATION GMBH (DE) | 2015-08-27 | — | — | US | disclosed |
| EP-2900681-A1 | REACTIVE, LIPOPHILIC NUCLEOSIDE BUILDING BLOCKS FOR THE SYNTHESIS OF HYDROPHOBIC NUCLEIC ACIDS | Ionovation GmbH (DE) | 2015-08-05 | — | — | EP | disclosed |
| US-20150202307-A1 | Colloid Bonded Medicinal Compounds | B. BRAUN MELSUNGEN AG (DE) | 2015-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190117798-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | HDLBP, APOB, TSG101 | KDM5A 4482/4885FAAH 3253/4885DNM1 1021/4885 |
| US-10556018-B2 | Compositions and methods for delivery of agents | HDLBP, APOB, TSG101 | KDM5A 4482/4885FAAH 3253/4885DNM1 1021/4885 |
| US-20200206362-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | HDLBP, APOB, TSG101 | KDM5A 4482/4885FAAH 3253/4885DNM1 1021/4885 |
| US-11285222-B2 | Compositions and methods for delivery of agents | HDLBP, APOB, TSG101 | KDM5A 4482/4885FAAH 3253/4885DNM1 1021/4885 |
| US-20220265857-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | HDLBP, APOB, TSG101 | KDM5A 4482/4885FAAH 3253/4885DNM1 1021/4885 |
| US-20150202307-A1 | Colloid Bonded Medicinal Compounds | ALB, EPCAM, SERPINA6 | KDM5A 4801/4885FAAH 3625/4885DNM1 2098/4885 |
| US-20150291649-A1 | 5-Fluorouracil Derivatives | DPYD, FAU, DHFR | KDM5A 1004/4885FAAH 3744/4885DNM1 2669/4885 |
| US-20150240295-A1 | REACTIVE, LIPOPHILIC NUCLEOSIDE BUILDING BLOCKS FOR THE SYNTHESIS OF HYDROPHOBIC NUCLEIC ACIDS | NCL, NOP2, POLRMT | KDM5A 4558/4885FAAH 3423/4885DNM1 766/4885 |
| US-20180028664-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | HDLBP, APOB, TSG101 | KDM5A 4482/4885FAAH 3253/4885DNM1 1021/4885 |
| US-20190175633-A1 | REACTIVE, LIPOPHILIC NUCLEOSIDE BUILDING BLOCKS FOR THE SYNTHESIS OF HYDROPHOBIC NUCLEIC ACIDS | NCL, NOP2, HNRNPD | KDM5A 4774/4885FAAH 2384/4885DNM1 1470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.