Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | CCR8 | P51685 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982003 | 0.92 | ALDH1A1 (0.42) | ALDH1A1MAPTKMT2ANPC1RAB9A | |
| Iodomethane SCHEMBL11687901 | 0.86 | ALDH1A1 (0.39) | ALDH1A1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL31691890 | 0.77 | HRH3 (0.43) | ALDH1A1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL8647354 | 0.77 | HRH3 (0.43) | ALDH1A1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL11777192 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL10632381 | 0.74 | POLB (0.34) | ALDH1A1MAPTKDM4EPOLBMAPK1 | |
| SCHEMBL31111388 | 0.73 | HRH3 (0.43) | ALDH1A1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL17594831 | 0.73 | MAPT (0.42) | ALDH1A1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL11183986 | 0.73 | GFER (0.36) | ALDH1A1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL531613 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150210641-A1 | NOVEL CYTOCHROME P450 INHIBITORS AND THEIR METHOD OF USE | CORTENDO AB (PUBL) | 2015-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210641-A1 | NOVEL CYTOCHROME P450 INHIBITORS AND THEIR METHOD OF USE | CYP11B1, CYP11B2, CYP27A1 | ALDH1A1 527/4885MAPT 3203/4885KMT2A 3047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.