Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.71 |
| ▸ | RAB9A | P51151 | 7/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.71 |
| ▸ | MEN1 | O00255 | 7/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.71 |
| ▸ | NPC1 | O15118 | 6/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.71 |
| ▸ | GAA | P10253 | 4/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 8/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL656187 | 0.94 | MAPT (0.80) | MAPTRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL8207063 | 0.83 | ALDH1A1 (0.84) | MAPTRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL654015 | 0.81 | ALDH1A1 (1.00) | MAPTRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL5344833 | 0.80 | MAPT (0.78) | MAPTRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL16689457 | 0.80 | MAPT (0.78) | MAPTRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL5432647 | 0.79 | MAPT (0.74) | MAPTRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL610929 | 0.79 | ALDH1A1 (0.76) | MAPTRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL1428039 | 0.73 | IKBKB (0.71) | MAPTRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL7054417 | 0.71 | TUBB4A (0.58) | MAPTRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL8143273 | 0.71 | GAA (0.60) | MAPTRAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2575969-A1 | ANTIVIRAL ACTIVITY OF NOVEL BICYCLIC HETEROCYCLES | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2013-04-10 | — | — | EP | disclosed |
| EP-2405973-A2 | THIAZOLOPYRIMIDINE MODULATORS AS IMMUNOSUPPRESSIVE AGENTS | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2012-01-18 | — | — | EP | disclosed |
| WO-2011147753-A1 | ANTIVIRAL ACTIVITY OF NOVEL BICYCLIC HETEROCYCLES | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U.LEUVEN R&D (BE) | 2011-12-01 | — | — | WO | disclosed |
| WO-2010103130-A2 | NOVEL BICYCLIC HETEROCYCLES | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U.LEUVEN R&D (BE) | 2010-09-16 | — | — | WO | disclosed |