Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 1.00 |
| ▸ | HPGD | P15428 | 8/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | GAA | P10253 | 7/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 5/20 | 1.00 |
| ▸ | RAB9A | P51151 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.80 |
| ▸ | NPC1 | O15118 | 2/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | IKBKB | O14920 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207063 | 0.89 | ALDH1A1 (0.84) | ALDH1A1HPGDMAPTGAAALOX15 | |
| SCHEMBL656187 | 0.86 | MAPT (0.80) | ALDH1A1HPGDMAPTGAAALOX15 | |
| SCHEMBL610929 | 0.86 | ALDH1A1 (0.76) | ALDH1A1HPGDMAPTGAAALOX15 | |
| SCHEMBL16689457 | 0.85 | MAPT (0.78) | ALDH1A1HPGDMAPTGAAALOX15 | |
| SCHEMBL5344833 | 0.85 | MAPT (0.78) | ALDH1A1HPGDMAPTGAAALOX15 | |
| SCHEMBL976420 | 0.84 | ALDH1A1 (0.72) | ALDH1A1HPGDMAPTGAAALOX15 | |
| SCHEMBL1563613 | 0.84 | GAA (1.00) | ALDH1A1HPGDMAPTGAAALOX15 | |
| SCHEMBL937185 | 0.83 | ALDH1A1 (0.71) | ALDH1A1HPGDMAPTGAAALOX15 | |
| SCHEMBL937896 | 0.83 | ALDH1A1 (0.71) | ALDH1A1HPGDMAPTGAAALOX15 | |
| SCHEMBL14882798 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HPGDMAPTGAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12559495-B2 | Purine diones as Wnt pathway modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2026-02-24 | — | — | US | disclosed |
| EP-4626875-A1 | ADAR1 INHIBITORS AND METHODS OF USING THE SAME | Avammune Therapeutics Inc. (US) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024116207-A1 | ADAR1 INHIBITORS AND METHODS OF USING THE SAME | AVAMMUNE THERAPEUTICS INC. (IN) | 2024-06-06 | — | — | WO | disclosed |
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-02-29 | — | — | US | disclosed |
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-02-29 | — | — | US | disclosed |
| US-11840527-B2 | Non-fused thiophene derivatives and their uses | ENYO PHARMA (FR) | 2023-12-12 | — | — | US | disclosed |
| CN-116514844-A | Thienopyrimidine derivatives and application thereof as pan KRAS mutation inhibitor | 思路迪生物医药(上海)有限公司 | 2023-08-01 | — | — | CN | disclosed |
| WO-2023138589-A1 | FIVE-MEMBERED HETEROCYCLIC PYRIMIDINE DERIVATIVE AND USE THEREOF AS INHIBITOR OF PAN-KRAS MUTATION | 思路迪生物医药(上海)有限公司 | 2023-07-27 | — | — | WO | disclosed |
| CN-116472292-A | Modified proteins and protein degrading agents | 上海睿跃生物科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| US-20230174533-A1 | PURINE DIONES AS WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-06-08 | — | — | US | disclosed |
| US-5521181-A | Bicyclic substituted hexahydrobenz[e]isoindole α-1 adrenergic antagonists | ABBOTT LABORATORIES (US) | 1996-05-28 | — | — | US | disclosed |
| WO-1995028405-A1 | BICYCLIC THIOPHENE DERIVATIVES AND USE AS GONADOTROPIN RELEASING HORMONE ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-26 | — | — | WO | disclosed |
| EP-0678577-A2 | Method for the production of recombinant human LH-RH receptor proteins | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-25 | — | — | EP | disclosed |
| US-5290921-A | Intermediates and colorants having primary hydroxyl enriched poly (oxyalkylene) moieties and their preparation | MILLIKEN RESEARCH CORPORATION (US) | 1994-03-01 | — | — | US | disclosed |
| EP-0234557-B1 | 3-(1H-Tetrazol-5-yl)thieno[2,3-d]pyrimidin-4(3H)-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-11-28 | — | — | EP | disclosed |
| EP-0202538-B1 | GROWTH PROMOTING AGENTS | BAYER AG (DE) | 1988-12-28 | — | — | EP | disclosed |
| US-4761474-A | 3-(1H-tetrazol-5-yl)thieno[2,3-d]pyrimidin-4(3H)-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-02 | — | — | US | disclosed |
| US-4692461-A | PLANT PROTECTION | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-08 | — | — | US | disclosed |
| EP-0234557-A1 | 3-(1H-Tetrazol-5-yl)thieno[2,3-d]pyrimidin-4(3H)-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0224140-A1 | Thienyl urea derivatives | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, MDM2 | ALDH1A1 1427/4885HPGD 3064/4885MAPT 3010/4885 |
| US-20230174533-A1 | PURINE DIONES AS WNT PATHWAY MODULATORS | WNT1, WNT3A, WNT3 | ALDH1A1 1754/4885HPGD 1793/4885MAPT 4782/4885 |
| US-11840527-B2 | Non-fused thiophene derivatives and their uses | FTH1, SLC40A1, FECH | ALDH1A1 1977/4885HPGD 1506/4885MAPT 2844/4885 |
| US-12559495-B2 | Purine diones as Wnt pathway modulators | WNT1, CTNND1, WNT3A | ALDH1A1 1125/4885HPGD 1773/4885MAPT 4457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.