SCHEMBL16950262

SCHEMBL16950262

O=C(O)c1cc(N2CCCC2)cc(C(=O)O)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.49
CSNK2B P67870 1/20 0.49
CSNK2A1 P68400 1/20 0.49
ALDH1A1 P00352 4/20 0.49
HSD17B10 Q99714 4/20 0.49
KDM4E B2RXH2 4/20 0.49
HPGD P15428 3/20 0.49
GAA P10253 3/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
TSHR P16473 4/20 0.48
ALOX15 P16050 3/20 0.48
HIF1A Q16665 1/20 0.48
GNE Q9Y223 1/20 0.47
IP6K1 Q92551 1/20 0.46
NPC1 O15118 1/20 0.42
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
MAPT P10636 1/20 0.42
STAT1 P42224 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21044592 0.83 ADRB1 (0.52) ALDH1A1HSD17B10KDM4ETSHRALOX15
SCHEMBL16950261 0.83 KMO (0.55) ALDH1A1KDM4EMEN1KMT2ALMNA
SCHEMBL19078867 0.82 ALDH1A1 (0.43) ALDH1A1HSD17B10KDM4EHPGDGAA
SCHEMBL3114523 0.80 KMO (0.52) ALDH1A1HSD17B10KDM4EHPGDMEN1
SCHEMBL30811691 0.79 KDM4E (0.45) CSNK2A2CSNK2BCSNK2A1ALDH1A1HSD17B10
SCHEMBL2533014 0.78 ALDH1A1 (0.51) CSNK2A2CSNK2BCSNK2A1ALDH1A1HSD17B10
SCHEMBL21044498 0.78 RAB9A (0.43) ALDH1A1KDM4EGAAMEN1KMT2A
SCHEMBL25136105 0.77 CSNK2A2 (0.41) CSNK2A2CSNK2BCSNK2A1ALDH1A1HSD17B10
SCHEMBL10098376 0.77 KDM4E (0.50) CSNK2A2CSNK2BCSNK2A1ALDH1A1HSD17B10
Hydrochloric Acid SCHEMBL14876289 0.75 KDM4E (0.49) ALDH1A1HSD17B10KDM4EHPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3191451-B1 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME OKINAWA INST SCIENCE & TECH SCHOOL CORP (JP) 2019-06-05 EP claimed
US-20170217889-A1 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) 2017-08-03 US claimed
EP-3191451-A1 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME Okinawa Institute of Science and Technology School Corporation (JP) 2017-07-19 EP claimed
WO-2016038890-A1 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) 2016-03-17 WO claimed
CN-104703805-B Luminescent lanthanide complexes, and articles and inks comprising the luminescent complexes 锡克拜控股有限公司 2016-12-28 CN disclosed
EP-2900478-B1 LUMINESCENT LANTHANIDE COMPLEX, AND ARTICLES AND INKS CONTAINING THE LUMINESCENT COMPLEX SICPA HOLDING SA (CH) 2016-07-27 EP disclosed
US-9163155-B2 Luminescent lanthanide complex, and articles and inks containing the luminescent complex SICPA HOLDING SA (CH) 2015-10-20 US disclosed
EP-2900478-A1 LUMINESCENT LANTHANIDE COMPLEX, AND ARTICLES AND INKS CONTAINING THE LUMINESCENT COMPLEX Sicpa Holding SA (CH) 2015-08-05 EP disclosed
CN-104703805-A Luminescent lanthanide complexes, and articles and inks comprising the luminescent complexes SICPA HOLDING SA 2015-06-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170217889-A1 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME PDK2, PKD1, PDHA2 CSNK2A2 1174/4885CSNK2B 2008/4885CSNK2A1 1149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.