Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HSD17B14 | Q9BPX1 | 3/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16957085 | 0.86 | ADRB1 (0.40) | ADRB1ADRA2AADRB3ADRA2BADRA2C | |
| SCHEMBL16954240 | 0.82 | CES2 (0.52) | MEN1KMT2AHPGDCES2BCHE | |
| SCHEMBL16953964 | 0.80 | KAT6A (0.39) | MEN1KMT2AHPGDHTTKDM4E | |
| SCHEMBL16953170 | 0.79 | TRPA1 (0.48) | MEN1KMT2ANPC1THRBHSD17B1 | |
| SCHEMBL16951295 | 0.79 | NPC1 (0.41) | ADRB1ADRA2AADRB3ADRA2BADRA2C | |
| SCHEMBL16959071 | 0.78 | CTSL (0.35) | NPC1HPGDCES2BCHECES1 | |
| SCHEMBL16951364 | 0.78 | CYP11B1 (0.40) | MEN1KMT2ATSHRCES2CES1 | |
| SCHEMBL16953106 | 0.78 | CES2 (0.31) | CES2BCHECES1 | |
| SCHEMBL16951986 | 0.78 | PDCD1 (0.35) | HPGDLMNACES2BCHECES1 | |
| SCHEMBL16958119 | 0.77 | KAT6A (0.44) | MEN1KMT2ALMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |