Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16960908 | 0.83 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPK1TDP1L3MBTL1 | |
| SCHEMBL16962116 | 0.81 | HTT (0.32) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL16951800 | 0.81 | HTT (0.35) | ALDH1A1HPGDMAPK1TDP1L3MBTL1 | |
| SCHEMBL15271315 | 0.80 | ALDH1A1 (0.39) | ALDH1A1HPGDMAPK1TDP1L3MBTL1 | |
| SCHEMBL16954915 | 0.80 | LMNA (0.36) | ALDH1A1HPGDL3MBTL1TSHRLMNA | |
| SCHEMBL16955354 | 0.79 | AMY1A (0.38) | ALDH1A1TDP1L3MBTL1TSHRLMNA | |
| SCHEMBL16956764 | 0.79 | MAOA (0.35) | ALDH1A1HPGDMAPK1TDP1L3MBTL1 | |
| SCHEMBL16953498 | 0.78 | HPGD (0.34) | ALDH1A1HPGDMAPK1TDP1L3MBTL1 | |
| SCHEMBL4311186 | 0.77 | ALDH1A1 (0.40) | ALDH1A1HPGDMAPK1TDP1L3MBTL1 | |
| SCHEMBL16954198 | 0.77 | HPGD (0.49) | ALDH1A1HPGDMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |