Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15771510 | 0.84 | LMNA (0.40) | LMNAHTTKMT2AMEN1MAPT | |
| SCHEMBL16959273 | 0.83 | CSNK2A1 (0.38) | LMNAHTTTSHRHPGDGAA | |
| SCHEMBL16962116 | 0.81 | HTT (0.32) | LMNAHTT | |
| SCHEMBL16951864 | 0.81 | KMT2A (0.37) | LMNAHTTKMT2AMEN1MAPT | |
| SCHEMBL16953333 | 0.80 | ALDH1A1 (0.34) | LMNAHTTMAPTPOLBTSHR | |
| SCHEMBL16960052 | 0.79 | ALDH1A1 (0.40) | LMNAKMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL16958565 | 0.79 | ALPL (0.33) | HTTTSHRHPGDGAAALDH1A1 | |
| SCHEMBL16958907 | 0.78 | KMT2A (0.40) | LMNAHTTKMT2AMEN1MAPT | |
| SCHEMBL11890397 | 0.77 | GABRA1 (0.39) | LMNAHTTKMT2AMEN1MAPT | |
| SCHEMBL16951022 | 0.77 | GAA (0.51) | LMNAKMT2AMEN1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |