Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | SCN1A | P35498 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147753 | 0.81 | SCN4A (0.54) | GRM5SCN4ALMNASCN1ASCN5A | |
| SCHEMBL9195589 | 0.81 | ALDH1A1 (0.42) | LMNATSHRKCNH2MAPTTDP1 | |
| SCHEMBL16953864 | 0.79 | LMNA (0.37) | GRM5LMNACYP3A4TSHRMAPT | |
| SCHEMBL21859573 | 0.79 | L3MBTL1 (0.40) | LMNACYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL16961008 | 0.78 | LMNA (0.39) | SCN4ALMNASCN1ASCN5ASCN9A | |
| SCHEMBL16957446 | 0.77 | APOBEC3G (0.41) | LMNATSHRSLC6A4MAPTTDP1 | |
| SCHEMBL16957443 | 0.75 | NPC1 (0.40) | LMNATSHRMAPTTDP1L3MBTL1 | |
| SCHEMBL16950519 | 0.75 | NPC1 (0.37) | LMNATSHRKCNH2MAPTTDP1 | |
| SCHEMBL16950516 | 0.75 | LMNA (0.35) | LMNATSHRMAPTTDP1NPSR1 | |
| SCHEMBL2522911 | 0.74 | ALDH1A1 (0.47) | GRM5SCN4ALMNASCN1ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |