Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955924 | 0.86 | RXRA (0.45) | KMT2AMEN1RXRARXRBRXRG | |
| SCHEMBL16959409 | 0.85 | EPHX2 (0.39) | EPHX2NR1H4F2RKMT2AMEN1 | |
| SCHEMBL16961715 | 0.84 | KMT2A (0.43) | KMT2AMEN1NQO1BRD4BRD2 | |
| SCHEMBL16955876 | 0.83 | CA1 (0.39) | EPHX2NR1H4F2RKMT2AMEN1 | |
| SCHEMBL16957459 | 0.83 | KAT6A (0.33) | NR1H4F2R | |
| SCHEMBL1190221 | 0.82 | CREBBP (0.47) | EPHX2NR1H4F2RKMT2AMEN1 | |
| SCHEMBL16955754 | 0.80 | GABRA1 (0.46) | KMT2AMEN1RXRARXRBRXRG | |
| SCHEMBL16958847 | 0.79 | CYP4F2 (0.40) | KMT2AMEN1RXRARXRBRXRG | |
| SCHEMBL25468623 | 0.78 | NQO1 (0.46) | EPHX2NR1H4KMT2AMEN1NQO1 | |
| SCHEMBL278323 | 0.78 | NQO1 (0.46) | EPHX2NR1H4KMT2AMEN1NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |