Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954338 | 0.83 | EPHX2 (0.37) | ALDH1A1LMNAMEN1EPHX2KMT2A | |
| SCHEMBL16952485 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPK1KDM4EGAANQO2 | |
| SCHEMBL16955754 | 0.83 | GABRA1 (0.46) | ALOX15MAPK1HSD17B10TDP1KDM4E | |
| SCHEMBL16958847 | 0.82 | CYP4F2 (0.40) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL16959449 | 0.82 | CA1 (0.44) | CA1CA2ALDH1A1LMNAALOX15 | |
| SCHEMBL16957459 | 0.80 | KAT6A (0.33) | MAPTNR1H4F2R | |
| SCHEMBL1189363 | 0.79 | MAPT (0.45) | CA1CA2ALDH1A1LMNAALOX15 | |
| SCHEMBL16953671 | 0.77 | CYP3A4 (0.38) | ALDH1A1KDM4EGAAMAPTTP53 | |
| SCHEMBL16958822 | 0.77 | RXRA (0.40) | CA2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL4729201 | 0.75 | RXRA (0.47) | CA1CA2ALDH1A1LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |