Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959875 | 0.85 | CYP4F2 (0.47) | CYP4F2CYP4A11CYP3A4BACE1LMNA | |
| SCHEMBL16959444 | 0.83 | CYP3A4 (0.41) | CYP4F2CYP4A11CYP3A4BACE1LMNA | |
| SCHEMBL16955876 | 0.82 | CA1 (0.39) | LMNAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL14488840 | 0.81 | CYP3A4 (0.47) | CYP4F2CYP4A11CYP3A4BACE1LMNA | |
| SCHEMBL16954338 | 0.79 | EPHX2 (0.37) | LMNAMEN1KMT2ASMN1; SMN2NR4A1 | |
| SCHEMBL16955754 | 0.79 | GABRA1 (0.46) | CYP3A4MAPTMEN1KMT2APOLB | |
| SCHEMBL16955368 | 0.79 | KMT2A (0.43) | CYP4F2CYP4A11CYP3A4BACE1LMNA | |
| SCHEMBL16953471 | 0.79 | LMNA (0.47) | CYP4F2CYP4A11CYP3A4BACE1LMNA | |
| SCHEMBL16950749 | 0.79 | CYP4F2 (0.42) | CYP4F2CYP4A11CYP3A4BACE1LMNA | |
| SCHEMBL16956217 | 0.78 | CYP4F2 (0.61) | CYP4F2CYP4A11CYP3A4BACE1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |