Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 8/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 3/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20836735 | 1.00 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL919577 | 0.84 | ALDH1A1 (0.55) | MEN1KMT2ATP53SMN1; SMN2KDM4E | |
| SCHEMBL16954598 | 0.83 | KMT2A (0.48) | MEN1KMT2ATP53SMN1; SMN2KDM4E | |
| SCHEMBL13725392 | 0.81 | RXRA (0.53) | MEN1KMT2ATP53SMN1; SMN2KDM4E | |
| SCHEMBL16533898 | 0.80 | CA1 (0.50) | MEN1KMT2ATP53SMN1; SMN2KDM4E | |
| SCHEMBL16957995 | 0.79 | MEN1 (0.43) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL16191959 | 0.78 | NQO2 (0.61) | MEN1KMT2ATP53SMN1; SMN2KDM4E | |
| SCHEMBL16191961 | 0.78 | NQO2 (0.61) | MEN1KMT2ATP53SMN1; SMN2KDM4E | |
| SCHEMBL16955368 | 0.77 | KMT2A (0.43) | MEN1KMT2ATP53SMN1; SMN2KDM4E | |
| SCHEMBL6194628 | 0.77 | CYP3A4 (0.55) | MEN1KMT2ATP53SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2796442-B1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | INST MED BIOTECHNOLOGY CAMS (CN) | 2019-03-27 | — | — | EP | claimed |
| US-20140371232-A1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2014-12-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371232-A1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | ACHE, GAP43, LNPK | PDE4A 1984/4885PDE4B 1737/4885PDE4C 1719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.