Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955924 | 0.85 | RXRA (0.45) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL16953371 | 0.85 | PLA2G2A (0.43) | ALDH1A1L3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL16959409 | 0.84 | EPHX2 (0.39) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL12128793 | 0.83 | RXRA (0.53) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL16961342 | 0.83 | RXRA (0.43) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL16954802 | 0.82 | SCN9A (0.46) | RXRARXRBRXRGNPSR1POLB | |
| SCHEMBL16951290 | 0.81 | KMT2A (0.46) | MEN1KMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL16952326 | 0.80 | PTGS1 (0.47) | RXRARXRBRXRGALDH1A1NOTUM | |
| SCHEMBL16959546 | 0.79 | L3MBTL1 (0.44) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL15561973 | 0.77 | CES2 (0.58) | RXRARXRBRXRGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |