Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955131 | 0.91 | PTPN1 (0.43) | ALOX5CYP4F2CYP4A11THRBPTPN1 | |
| SCHEMBL16955768 | 0.85 | CYP4F2 (0.44) | ALOX5CYP4F2CYP4A11PTGS2PTPN1 | |
| SCHEMBL16951084 | 0.80 | PTGS2 (0.53) | PTGS2GPR84CA1CA2CA9 | |
| SCHEMBL462587 | 0.80 | ALOX5 (0.57) | ALOX5CYP4F2CYP4A11THRBPTGS2 | |
| SCHEMBL16958037 | 0.79 | LMNA (0.46) | CYP4F2CYP4A11CA9ALDH1A1HSD17B10 | |
| SCHEMBL16958216 | 0.79 | RAB9A (0.38) | PTGS2CA1CA2CA9MAPK1 | |
| SCHEMBL16956038 | 0.79 | CNR1 (0.40) | PTGS2MAPK1RAB9AALDH1A1LMNA | |
| SCHEMBL16952426 | 0.79 | CYP4F2 (0.59) | ALOX5CYP4F2CYP4A11THRBPTGS2 | |
| SCHEMBL16950784 | 0.78 | CYP4F2 (0.41) | ALOX5CYP4F2CYP4A11PTGS2MAPK1 | |
| SCHEMBL16953130 | 0.78 | ALOX5 (0.46) | ALOX5CYP4F2CYP4A11THRBPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |